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Evidence suggests Antioxidants maydecreaseInflammation.

44 studies (45 claims)

Strong consensus

Study Claims

41 of 47
InterventionDirectionEndpointTypePopulationDosageTitle
novel nutritional formula (NNF) enriched in eicosapentaenoic (EPA) and gamma-linolenic fatty acids and antioxidantsDecreases - reducesairway inflammation
Human
critically ill patientsDaily consumption (exact dosage not specified).Impact of a novel nutritional formula on asthma control and biomarkers of allergic airway inflammation in children.cited 29×
antioxidants with polyphenolsDecreases - are considered useful as adjuvant therapyinflammation and oxidative stress
Human
patients with type 2 diabetes mellitusNot specifiedPotential Benefits of Antioxidant Phytochemicals in Type 2 Diabetes.cited 17×
antioxidants including polyphenolsDecreases - decreaseinflammation
Human
Not specifiedOxidative stress and post-stroke depression: possible therapeutic role of polyphenols?cited 47×
A diet rich in antioxidantsDecreases - can result in preventioninflammation-related pathologies
Human
nullNot specified.Comprehensive and critical view on the anti-inflammatory and immunomodulatory role of natural phenolic antioxidants.cited 9×
Phenolic antioxidantsDecreases - exerting anti-inflammatory effectinflammation
Human
nullNot specified.Comprehensive and critical view on the anti-inflammatory and immunomodulatory role of natural phenolic antioxidants.cited 9×
Phenolic antioxidantsDecreases - potential of phenolics as inflammation antagonistsinflammation
Human
nullNot specified.Comprehensive and critical view on the anti-inflammatory and immunomodulatory role of natural phenolic antioxidants.cited 9×
antioxidantsDecreases - participate in reducing cutaneous inflammationcutaneous inflammation
Human
Not specifiedDermocosmetic management of hyperpigmentations.cited 10×
antioxidantsDecreases - protect cells from damagedamage caused by oxidative stress and its associated pathological conditions including inflammation
Human
cellsNot specifiedAntioxidants for prostate cancer chemoprevention: challenges and opportunities.cited 34×
antioxidantsDecreases - prevented these alterationsendothelial dysfunction, oxidative stress, DNA damages, inflammation
HumanMolecular
endothelial cellsLipodystrophy-linked LMNA p.R482W mutation induces clinical early atherosclerosis and in vitro endothelial dysfunction.
antioxidantsDecreases - preventinginflammation
Human
Not specifiedSystemic antioxidants and skin health.cited 7×
AntioxidantsDecreases - can have anti-inflammatory effectsinflammation
Human
Not specifiedDietary interventions in asthma.cited 16×
antioxidantsDecreases - apparent ability to ameliorateinflammation
Human
Not specifiedThe role of inflammatory biomarkers in developing targeted cardiovascular therapies: lessons from the cardiovascular inflammation reduction trials.cited 33×
AntioxidantsDecreases - demonstrated potential benefits in reducinginflammation
Human
patients with COPDNot specifiedThe genomic landscape of chronic obstructive pulmonary disease: Insights from nutrigenomics.cited 1×
antioxidantsDecreases - gained utmost importance because of their potential as prophylactic and therapeutic agentsinflammation
Human
Not specifiedEncapsulation of antioxidants in gastrointestinal-resistant nanoparticulate carriers.cited 26×
antioxidantsDecreases - have anti-inflammatory properties, which could be beneficial in reducinginflammation associated with diabetes
Human
Not specifiedDiabetes and the associated complications: The role of antioxidants in diabetes therapy and care.cited 4×
antioxidantsDecreases - decreasedlevels of markers of inflammation and oxidative stress
Human
experimental models of MSNot specifiedAntioxidant Therapies in the Treatment of Multiple Sclerosis.cited 1×
AntioxidantsDecreases - counteractoxidative damage and inflammation
Human
Not specifiedGuardians of Oral Health: Antioxidants as Promising Allies in Periodontal Wellness.
antioxidantsDecreases - exhibit antioxidative and anti-inflammatory propertiesoxidative stress and inflammation
Human
Not specifiedTargeting Metabolic Diseases: The Role of Nutraceuticals in Modulating Oxidative Stress and Inflammation.cited 28×
antioxidants (vitamin E)Decreases - targetingoxidative stress, inflammation and injury
Human
patients with NAFLDNot specifiedCurrent and upcoming pharmacotherapy for non-alcoholic fatty liver disease.cited 324×
antioxidantsDecreases - reducingpain and inflammation
Human
chronic pancreatitis patientsAntioxidants are not useful in reducing both pain and inflammation in chronic pancreatitis.cited 4×
antioxidantsNo effect - no effectpain and inflammation
Human
chronic pancreatitis patientsAntioxidants are not useful in reducing both pain and inflammation in chronic pancreatitis.cited 4×
antioxidantsNo effect - little evidence for an effectT2 inflammation
Human
adults and adolescents with asthmaNot specifiedEffect of dietary interventions on markers of type 2 inflammation in asthma: A systematic review.cited 4×
antioxidantsDecreases - a potential therapythe amplification of inflammation
Human
Not specifiedLecithinized superoxide dismutase in the past and in the present: Any role in the actual pandemia of COVID-19?cited 11×
AntioxidantsDecreases - show inhibitionvarious metabolic enzymes and factors responsible for inflammation
Molecular
Not specifiedOptimized and comparative antioxidant assays and its applications in herbal and synthetic drug analysis as an antioxidants.cited 11×
antioxidantsDecreases - blockedVCAM-1 signal transduction and VCAM-1-dependent inflammation
HumanMolecular
Not specifiedVascular cell adhesion molecule-1 expression and signaling during disease: regulation by reactive oxygen species and antioxidants.cited 409×
an oral health optimized diet low in carbohydrates, rich in Omega-3 fatty acids, and rich in vitamins C and D, antioxidants and fiberDecreases - significantly reducedgingival and periodontal inflammation
Human
Not specified (dietary intake, not isolated supplement).An oral health optimized diet can reduce gingival and periodontal inflammation in humans - a randomized controlled pilot study.cited 124×
plant-derived antioxidants (silymarin, silibinin, curcumin, resveratrol, berberine, quercetin)Decreases - help decreasemetabolic endotoxemia, intestinal permeability, and gut inflammation
Human
experimental modelsNot specifiedHepatocellular Interactions of Potential Nutraceuticals in the Management of Inflammatory NAFLD.cited 3×
oral supplementation with a combined formulation of antioxidants and essential polyunsaturated fatty acidsAffects - changeddifferences in inflammation biomarkers
Human
patients with DEDs or primary open-angle glaucomaPatients undergoing long-term treatment with antihypertensive eye drops responded positively with respect to their ocular surface disorder to oral supplementation with antioxidants and essential fatty acids.cited 43×
decreased antioxidantsIncreases - lead toinflammation
Human
Not specifiedReactive oxygen species as the molecular modulators of calcium oxalate kidney stone formation: evidence from clinical and experimental investigations.cited 256×
Natural antioxidants contained in edible or medicinal plantsDecreases - possess strong antioxidant and free radical scavenging abilities as well as anti-inflammatory actionoxidative stress and inflammation
Human
Not specifiedThe Role of Oxidative Stress and Antioxidants in Liver Diseases.cited 971×
Key components of the Mediterranean diet (MD)-including microbiota-accessible carbohydrates, omega-3 fatty acids, polyphenols, and antioxidantsDecreases - have demonstrated promise in reducingintestinal inflammation
Human
Not specifiedFrom Evidence to Practice: A Narrative Framework for Integrating the Mediterranean Diet into Inflammatory Bowel Disease Management.cited 1×
different dietary regimens, fiber intake, immunonutrients, and antioxidantsNo effect - have the potential to either exacerbate or mitigatechronic inflammation
Human
Not specifiedPancreatic Ductal Adenocarcinoma and Nutrition: Exploring the Role of Diet and Gut Health.cited 4×
Enteral nutrition enriched with eicosapentaenoic acid, γ-linolenic acid and antioxidants (eicosapentaenoic acid + γ-linolenic acid)Decreases - reduceinflammation
Human
adultsNot specifiedNutritional immunomodulation in critically ill children with acute lung injury: feasibility and impact on circulating biomarkers.cited 16×
antioxidants through diet or oral supplementationDecreases - can counteract the harmful effectsharmful effects of reactive oxygen species accumulated secondary to oxidative stress, ischemia, and inflammation
Human
Not specifiedAntioxidants and neurodegenerative eye disease.cited 4×
Antioxidants (AO) supplementationNo effect - has no addition benefit over PLOS and inflammation
Human
patients with CPDaily combined antioxidants (specific amounts not detailed)Antioxidants for Pancreatic Functions in Chronic Pancreatitis: A Double-blind Randomized Placebo-controlled Pilot Study.cited 18×
high intake of antioxidantsDecreases - may reduceairway inflammation
Human
elite athletesNot specifiedMechanisms and management of exercise-induced asthma in elite athletes.cited 19×
increasing the levels of antioxidant enzymes by activating the Nrf2 pathway together with simultaneous administration of dietary and endogenous antioxidantsDecreases - may be achievedreduce oxidative stress and inflammation at the same time
HumanAnimal
Not specifiedOxidative and Inflammatory Events in Prion Diseases: Can They Be Therapeutic Targets?cited 19×
use of antioxidantsDecreases - might be usefulprevent inflammation
Human
Not specifiedHyperuricemia and Atrial Fibrillation.cited 48×
these antioxidantsDecreases - reductioninflammation
Molecular
New insights into antioxidant strategies against paraquat toxicity.cited 172×
Cosmeceuticals that contain both antioxidants and anti-inflammatoriesDecreases - can help reducepostprocedure inflammation
Human
Not specifiedFacial rejuvenation: combining cosmeceuticals with cosmetic procedures.cited 4×
supplementation of exogenous antioxidantsIncreases - strengthenskin defense mechanisms against oxidation and inflammation
Human
skinNot specifiedQuercetin topical application, from conventional dosage forms to nanodosage forms.cited 54×