2
6
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↓6
—0
Evidence suggests Alcohol maydecreaseProliferation.
8 studies (8 claims)
Emerging evidence
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| Statins and isoprenoids, including tocotrienols, geraniol, limonene, β-ionone and perillyl alcohol | Decreases - synergistically suppress | cell proliferation and associated signaling pathways | AnimalMolecular | cancer cells derived from breast, colon, liver, mesothelium, prostate, pancreas, and skin | — | The Potential of Isoprenoids in Adjuvant Cancer Therapy to Reduce Adverse Effects of Statins. |
| Alcohol abuse and adherence to atherogenic diet (AD) | Increases - could play a role in the up-regulation of vascular smooth muscle cell proliferation-related gene expression | vascular smooth muscle cell proliferation-related gene expression | Animal | mice with hyperlipidemia | — | Alcohol Consumption in Combination with an Atherogenic Diet Increased Indices of Atherosclerosis in Apolipoprotein E/Low-Density Lipoprotein Receptor Double-Knockout Mice. |
| saffron alcohol extract | Decreases - can suppress the proliferation | proliferation of CT26 and HCT116 cells | AnimalMolecular | CT26 and HCT116 cells | Not specified | Saffron improves the efficacy of immunotherapy for colorectal cancer through the IL-17 signaling pathway.cited 4× |
| cholestatic liver fibrosis and subsequent alcohol exposure (DDC + EtOH) | Increases - exhibited | ductular proliferation | Animal | mice | Up to 24 g/kg of ethyl alcohol in a high-fat diet. | A Novel Mouse Model of Acute-on-Chronic Cholestatic Alcoholic Liver Disease: A Systems Biology Comparison With Human Alcoholic Hepatitis.cited 9× |
| Patchouli alcohol (PA) | Decreases - showed the inhibition of | GC cell proliferation | HumanMolecular | GC cells | — | Regulatory Mechanism and Experimental Verification of Patchouli Alcohol on Gastric Cancer Cell Based on Network Pharmacology.cited 11× |
| Patchouli alcohol (PA) | Decreases - suppressed proliferation | proliferation | HumanAnimalMolecular | Caco-2 human colorectal cancer cells | — | Preventive Activity of Patchouli Alcohol Against Colorectal Cancer and Diabetes.cited 4× |
| Patchouli alcohol (PA) | Decreases - inhibited | proliferation | Molecular | A549 and VCR-resistant A549/V16 NSCLC cells | — | Patchouli alcohol induces G0 /G1 cell cycle arrest and apoptosis in vincristine-resistant non-small cell lung cancer through ROS-mediated DNA damage.cited 9× |
| Patchouli alcohol (PA) | Decreases - selectively inhibited | proliferation of B16F10 cells | Molecular | B16F10 cells | — | The effects of patchouli alcohol and combination with cisplatin on proliferation, apoptosis and migration in B16F10 melanoma cells.cited 7× |