2
3
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↓3
—0
Evidence suggests Alcohol maydecreaseNitric oxide levels.
4 studies (5 claims)
Emerging evidence
Study Claims
| Intervention | Direction | Endpoint | Type | Population | Dosage | Title |
|---|---|---|---|---|---|---|
| alcohol exposure | Increases - increases | levels of reactive oxygen species (ROS; superoxide and hydroxyl radical) and nitric oxide (NO) | HumanMolecular | brain endothelial cells | — | Stabilization of superoxide dismutase by acetyl-l-carnitine in human brain endothelium during alcohol exposure: novel protective approach. |
| patchouli alcohol (PA) | Increases - significantly increased | expression of mRNA and protein of neuronal nitric oxide synthase (nNOS) and endothelial nitric oxide synthase (eNOS) | Animal | rat corpus cavernosum | — | Relaxation Effect of Patchouli Alcohol in Rat Corpus Cavernous and Its Underlying Mechanisms.cited 3× |
| Patchouli alcohol (PA) | Decreases - reversed the increased | mRNA expression of inducible nitric oxide synthase (iNOS) | Molecular | LPS-stimulated RAW264.7 cells | — | Anti-inflammatory effect of patchouli alcohol isolated from Pogostemonis Herba in LPS-stimulated RAW264.7 macrophages.cited 72× |
| Patchouli alcohol (PA) | Decreases - decreased | production of nitric oxide (NO) | Molecular | LPS-stimulated RAW264.7 cells | — | Anti-inflammatory effect of patchouli alcohol isolated from Pogostemonis Herba in LPS-stimulated RAW264.7 macrophages.cited 72× |
| (-)-Patchouli alcohol (PA) | Decreases - markedly attenuated the secretion | nitric oxide (NO) | Molecular | HPU-stimulated GES-1 cells | — | (-)-Patchouli alcohol protects against Helicobacter pylori urease-induced apoptosis, oxidative stress and inflammatory response in human gastric epithelial cells.cited 32× |