Alcohol
→Gene expression changes

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Evidence suggests Alcohol mayincreaseGene expression changes.

5 studies (7 claims)

Emerging evidence

Study Claims

7 of 8

Intervention	Direction	Endpoint	Type	Population	Dosage	Title
chronic alcohol feeding	No effect - did not affect	gene expression of HMG-CoA synthase	Animal	rats	—	Proteasome inhibitor treatment reduced fatty acid, triacylglycerol and cholesterol synthesis.
increasing alcohol dose	Increases - represent adaptive changes in response	brain gene expression	Animal	C57BL/6J male mice	—	Molecular profiles of drinking alcohol to intoxication in C57BL/6J mice.
voluntary alcohol consumption	Increases - resulted in small but consistent changes	brain gene expression	Animal	C57BL/6J male mice	—	Molecular profiles of drinking alcohol to intoxication in C57BL/6J mice.
voluntary alcohol consumption	Increases - occurred in a dose-dependent manner	brain gene expression changes	Animal	C57BL/6J male mice	—	Molecular profiles of drinking alcohol to intoxication in C57BL/6J mice.
Alcohol abuse and adherence to atherogenic diet (AD)	Increases - could play a role in the up-regulation of endothelial dysfunction-related gene expression	endothelial dysfunction-related gene expression	Animal	mice with hyperlipidemia	—	Alcohol Consumption in Combination with an Atherogenic Diet Increased Indices of Atherosclerosis in Apolipoprotein E/Low-Density Lipoprotein Receptor Double-Knockout Mice.
Alcohol abuse and adherence to atherogenic diet (AD)	Increases - could play a role in the up-regulation of vascular smooth muscle cell proliferation-related gene expression	vascular smooth muscle cell proliferation-related gene expression	Animal	mice with hyperlipidemia	—	Alcohol Consumption in Combination with an Atherogenic Diet Increased Indices of Atherosclerosis in Apolipoprotein E/Low-Density Lipoprotein Receptor Double-Knockout Mice.
patchouli alcohol (PA)	Decreases - down-regulating	gene expression levels of ureB, ureE, ureI and nixA	Molecular	H. pylori	—	Effect of patchouli alcohol on macrophage mediated Helicobacter pylori digestion based on intracellular urease inhibition.cited 17×