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A fasting and vegetarian diet treatment trial on chronic inflammatory disorders.

Acta dermato-venereologica
May 5, 1983
H Lithell et al. (10 authors)
Journal ArticleResearch Support, Non-U.S. Gov'tHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the effects of a vegetarian diet on arthritis and skin diseases, comparing outcomes during a modified fast and a subsequent vegetarian diet period.

Results Summary

During fasting, arthralgia improved in many subjects, and some skin conditions (pustulosis palmaris et plantaris and atopic eczema) showed improvement. However, symptoms returned for most patients during the vegetarian diet, except for some psoriasis cases. Serum lactoferrin levels correlated with symptom changes.

Population

Twenty patients with arthritis and various skin diseases.

Effective Dosage

Not specified

Duration

2-week modified fast followed by 3-week vegetarian diet.

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
modified fast
decrease
arthralgia
patients with arthritis and various skin diseases
-
was less intense
#1
modified fast
decrease
pustulosis palmaris et plantaris and atopic eczema
patients with arthritis and various skin diseases
-
an improvement could be demonstrated
#2
vegan diet
increase
both signs and symptoms
patients with arthritis and various skin diseases
-
returned
#3
vegan diet
decrease
psoriasis
some patients with psoriasis
-
experienced an improvement
#4
-
decrease
concentrations of lactoferrin in serum
most cases
-
fell to normal values
#5
-
neutral
improvement or impairment of signs and symptoms
-
-
was related to
#6
Abstract

Twenty patients with arthritis and various skin diseases were studied on a metabolic ward during a 2-week period of modified fast followed by a 3-week period of vegetarian diet. During fasting, arthralgia was less intense in many subjects. In some types of skin diseases (pustulosis palmaris et plantaris and atopic eczema) an improvement could be demonstrated during the fast. During the vegan diet, both signs and symptoms returned in most patients, with the exception of some patients with psoriasis who experienced an improvement. The concentrations of lactoferrin in serum reflect the turnover and activity of neutrophil leukocytes. When this protein was initially increased it fell to normal values in most cases. The improvement or impairment of signs and symptoms was related to the lactoferrin levels in serum.

Medical Subject Headings (MeSH)
AdultArthritisChronic DiseaseDermatitis, AtopicDiet, VegetarianFastingFemaleHumansInflammationMaleMiddle AgedPsoriasisRosaceaSkin Diseases
Study Links
PubMed ID6197838
Quality Scores
SafetyNot Assessed
Efficacy60/10
Quality50/10
Citation Metrics
Total Citations52
Citations/Year1.2
Relative Citation Ratio1.84
NIH Percentile71.9%
Research Impact Scores
APT Score0.75
Weight Score0.17
Normalized Score0.54
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