[Mechanism research progress on acupuncture-moxibustion therapy for functional gastrointestinal disorders: review and prospects].
Study Goal
The researchers aimed to review recent evidence on how acupuncture-moxibustion therapy alleviates symptoms of functional gastrointestinal disorders (FGIDs) and explore its potential mechanisms.
Results Summary
The study found that acupuncture-moxibustion therapy can improve FGID symptoms by regulating gastrointestinal motility, modulating visceral hypersensitivity, improving mucosal barrier function, balancing gut microbiota, and adjusting the gut-brain axis. However, the molecular mechanisms and specific disease targets remain unclear, and future research is needed to fully elucidate these aspects.
Population
Patients with functional gastrointestinal disorders (FGIDs) (specific demographics not detailed).
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
acupuncture-moxibustion therapy | decrease | symptoms of functional gastrointestinal disorders (FGIDs) | - | - | ameliorate | #1 |
acupuncture-moxibustion therapy | decrease | FGIDs symptoms | - | - | alleviate | #2 |
acupuncture-moxibustion therapy | neutral | gastrointestinal motility | - | - | regulating | #3 |
acupuncture-moxibustion therapy | neutral | visceral hypersensitivity | - | - | modulating | #4 |
acupuncture-moxibustion therapy | increase | impaired gastric-duodenal mucosal barrier | - | - | improving | #5 |
acupuncture-moxibustion therapy | decrease | inflammation | - | - | improving | #6 |
acupuncture-moxibustion therapy | neutral | intestinal microbiota | - | - | balancing | #7 |
acupuncture-moxibustion therapy | neutral | gut-brain axis | - | - | adjusting | #8 |
Acupuncture-moxibustion therapy has been known to ameliorate the symptoms of functional gastrointestinal disorders (FGIDs), although its mechanism remains unclear. The paper reviews the articles on acupuncture-moxibustion therapy for FGIDs in recent 5 years, and it is revealed that acupuncture-moxibustion therapy can alleviate FGIDs symptoms through regulating gastrointestinal motility, modulating visceral hypersensitivity, improving the impaired gastric-duodenal mucosal barrier and inflammation, balancing intestinal microbiota, and adjusting the gut-brain axis. Currently, the molecular mechanism of acupuncture-moxibustion therapy remains unknown for FGIDs, the specific disease target is not identified, and the interaction among various molecules is not elucidated adequately. The researches in the future should employ advanced technologies and methodologies to comprehensively and deeply explore and clarify the mechanism of acupuncture- moxibustion therapy for FGIDs.