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Acupuncture and moxibustion as effective treatments for simple obesity in children: a meta-analysis.

American journal of translational research
May 5, 2025
Fanghan Cui
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to systematically evaluate the effectiveness of acupuncture and moxibustion in treating simple obesity in children, focusing on metabolic and weight-related outcomes.

Results Summary

The study found that acupuncture and moxibustion significantly improved blood lipids, fasting blood glucose, BMI, and TCM syndrome scores in children with simple obesity. However, high heterogeneity (I² > 80%) in some outcomes suggests variability in study designs or populations.

Population

Children with simple obesity (studies published between 2003 and 2024).

Effective Dosage

Not specified in the abstract.

Duration

Not specified in the abstract.

Interactions

None mentioned.

Extracted Claims (10)
InterventionDirectionEndpointPopulationDosageImpactClaim #
acupuncture and moxibustion
decrease
total cholesterol (TC)
children with simple obesity
SMD = -0.53; 95% CI: -0.95 to -0.12, P<0.0001, I2 = 87.3%
significantly reduced
#1
acupuncture and moxibustion
decrease
triglyceride (TG)
children with simple obesity
SMD = -0.27; 95% CI: -0.54 to -0.01, P = 0.002, I2 = 66.7%
significantly reduced
#2
acupuncture and moxibustion
decrease
fasting blood glucose levels
children with simple obesity
SMD = -0.61; 95% CI: -1.08 to -0.13, I2 = 82.2%, P = 0.001
significantly reduced
#3
semaglutide combined with metformin
decrease
body mass indexes (BMI)
children with simple obesity
SMD = -0.49, 95% CI: -0.80 to -0.18, I2 = 81%
led to significant reductions
#4
acupuncture treatment
decrease
TCM syndrome scores
children with simple obesity
SMD = -1.49; 95% CI = -2.73 to 0.25; I2 = 96.4%, P<0.0001
resulted in a decrease
#5
acupuncture and moxibustion treatment
decrease
fasting blood glucose
children with simple obesity
-
significantly reduced
#6
acupuncture and moxibustion treatment
decrease
waist circumference
children with simple obesity
-
significantly reduced
#7
acupuncture and moxibustion treatment
decrease
TCM syndromes score
children with simple obesity
-
significantly reduced
#8
acupuncture and moxibustion treatment
decrease
BMI
children with simple obesity
-
significantly reduced
#9
acupuncture and moxibustion treatment
decrease
lipid levels
children with simple obesity
-
significantly reduced
#10
Abstract

OBJECTIVE: To systematically review published studies on the application of acupuncture and moxibustion in the treatment of simple obesity in children and evaluate its effectiveness. METHODS: A comprehensive search was conducted in the Wanfang, CNKI, Chinese Biomedical Literature, VIP, Embase, PubMed, Cochrane Library, and Web of Science for studies on the effects of acupuncture and moxibustion in treating simple obesity in children, published between December 2003 and October 2024. Primary clinical outcomes included blood lipids, fasting blood glucose, fasting insulin, weight-related indicators, clinical effects, leptin, body fat-related indicators, and traditional Chinese medicine (TCM) syndromes. Data were extracted and summarized, and a meta-analysis was performed using Revman 5.3 software and Stata 13.1. RESULTS: A total of 20 studies met the inclusion criteria, all involving acupuncture and moxibustion therapy. Compared with the control group, acupuncture and moxibustion significantly reduced total cholesterol (TC) (SMD = -0.53; 95% CI: -0.95 to -0.12, P<0.0001, I2 = 87.3%), triglyceride (TG) (SMD = -0.27; 95% CI: -0.54 to -0.01, P = 0.002, I2 = 66.7%), and fasting blood glucose levels (SMD = -0.61; 95% CI: -1.08 to -0.13, I2 = 82.2%, P = 0.001). Compared to metformin group, semaglutide combined with metformin led to significant reductions in body mass indexes (BMI) (SMD = -0.49, 95% CI: -0.80 to -0.18, I2 = 81%). Additionally, acupuncture treatment resulted in a decrease in TCM syndrome scores compared to control therapy (SMD = -1.49; 95% CI = -2.73 to 0.25; I2 = 96.4%, P<0.0001). CONCLUSION: Acupuncture and moxibustion treatment for simple obesity in children significantly reduced fasting blood glucose, waist circumference, TCM syndromes score, BMI and lipid levels.

Study Links
Quality Scores
SafetyNot Assessed
Efficacy80/10
Quality70/10
Research Impact Scores
APT Score0.05
Weight Score2.40
Normalized Score0.66
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