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Exercise Therapy, Systemic Acupuncture and Silicon Oxide Tablets in the Rehabilitation of Physical and Functional Disorders in Breast Cancer Survivors: Randomized Clinical Trial.

Asian Pacific journal of cancer prevention : APJCP
March 1, 2025
Patricia Santolia Giron et al. (6 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to compare the effectiveness of acupuncture versus exercise therapy and silicon oxide tablets in improving pain, depression, upper limb function, and range of motion in women who underwent breast cancer surgery.

Results Summary

Acupuncture showed significant improvements in pain, depressive symptoms, shoulder function, and range of motion over time, but no statistical difference was found between acupuncture and the other treatments. The study did not report adverse effects or safety concerns.

Population

Seventy-nine women with post-breast cancer surgery pain (VAS > 3), of whom 67 completed the study (23 in the acupuncture group).

Effective Dosage

Not specified (only mentions treatment sessions).

Duration

Ten treatment sessions (duration per session not specified).

Interactions

None mentioned.

Extracted Claims (12)
InterventionDirectionEndpointPopulationDosageImpactClaim #
exercise therapy
decrease
pain
women undergoing breast cancer surgery
-
improvement
#1
acupuncture
decrease
pain
women undergoing breast cancer surgery
-
improvement
#2
silicon oxide tablets (Stiper®)
decrease
pain
women undergoing breast cancer surgery
-
improvement
#3
exercise therapy
decrease
depressive symptoms
women undergoing breast cancer surgery
-
statistically significant difference
#4
acupuncture
decrease
depressive symptoms
women undergoing breast cancer surgery
-
statistically significant difference
#5
silicon oxide tablets (Stiper®)
decrease
depressive symptoms
women undergoing breast cancer surgery
-
statistically significant difference
#6
exercise therapy
increase
shoulder function
women undergoing breast cancer surgery
-
significant differences
#7
acupuncture
increase
shoulder function
women undergoing breast cancer surgery
-
significant differences
#8
silicon oxide tablets (Stiper®)
increase
shoulder function
women undergoing breast cancer surgery
-
significant differences
#9
exercise therapy
increase
range of motion (ROM)
women undergoing breast cancer surgery
-
statistically significant difference
#10
acupuncture
increase
range of motion (ROM)
women undergoing breast cancer surgery
-
statistically significant difference
#11
silicon oxide tablets (Stiper®)
increase
range of motion (ROM)
women undergoing breast cancer surgery
-
statistically significant difference
#12
Abstract

OBJECTIVE: To compare three rehabilitation treatments, exercise therapy, acupuncture, and silicon oxide tablets (Stiper®), in women undergoing breast cancer surgery, assessing pain, depression, upper limb function, and range of motion parameters (ROM). METHODS: Seventy-nine women with pain above 3 on the visual analog pain scale (VAS) were divided into three groups: exercise group was treated with exercise therapy, acupuncture group was treated with acupuncture, and Stiper® group was treated with silicon oxide tablets in place of needles. RESULTS: Sixty-seven patients completed the treatment, 26 from exercise group, 23 from acupuncture group, and 18 from Stiper® group . There was an improvement of pain over time in all groups, the first session compared with the fifth (p < 0.001) and with the tenth (p < 0.001), but not between groups. There was a statistically significant difference in depressive symptoms using the Beck questionnaire over time in the three groups, between the first and tenth sessions (p = 0.001), between the first and fifth sessions (p = 0.052), but not between groups. Regarding the DASH questionnaire for shoulder function, there were significant differences over time at all evaluated moments (p<0.001), but not between groups. There was a statistically significant difference in ROM over time in the three groups, but not between groups. CONCLUSION: The rehabilitation of physical dysfunctions in women who survived breast cancer through exercise therapy, acupuncture, and silicon oxide tablets in pain, depression, upper limb function, and ROM, proved to be effective, without statistical difference between the groups.

Medical Subject Headings (MeSH)
HumansFemaleBreast NeoplasmsMiddle AgedCancer SurvivorsAcupuncture TherapyExercise TherapyRange of Motion, ArticularSilicon DioxideFollow-Up StudiesPrognosisAdultTabletsQuality of LifePain Measurement
Study Links
Quality Scores
SafetyNot Assessed
Efficacy70/10
Quality70/10
Research Impact Scores
APT Score0.05
Weight Score2.40
Normalized Score0.62
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