Application and Mechanism of Action of a Ketogenic Diet in Antiepileptic Therapy.
Study Goal
The researchers aimed to review the possible mechanisms by which the ketogenic diet exerts a protective effect on epilepsy.
Results Summary
The study suggests that the ketogenic diet can treat drug-refractory epilepsy by regulating metabolism and may improve patients' cognition, behavior, and sleep quality. However, the exact therapeutic mechanism remains unclear.
Population
Patients with drug-refractory epilepsy.
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
ketogenic diet | decrease | drug-refractory epilepsy | epilepsy patients | - | can treat | #1 |
ketogenic diet | increase | quality of life | epilepsy patients | - | can enhance | #2 |
ketogenic diet | increase | cognition | epilepsy patients | - | improving | #3 |
ketogenic diet | increase | behavior | epilepsy patients | - | improving | #4 |
ketogenic diet | increase | sleep quality | epilepsy patients | - | improving | #5 |
ketogenic diet | decrease | epilepsy | - | - | exerts a protective effect on | #6 |
Epilepsy is a chronic neurological disorder caused by abnormal discharges of neurons in the brain, which seriously affects the quality of life of patients. Although there are various drug treatments available, many epilepsy patients still experience seizures with the effect of drugs and develop refractory epilepsy. The ketogenic diet can treat drug-refractory epilepsy by regulating the body's metabolism and can enhance the quality of life by improving their cognition, behavior, and sleep quality. However, there is no unified conclusion on the mechanism through which the ketogenic diet plays a therapeutic role in epilepsy. This article provides a review of the possible mechanisms of how the ketogenic diet exerts a protective effect on epilepsy.