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Effects of exercise based cardiac rehabilitation delivery modes on chronic heart failure: a systematic review and network meta-analysis.

Scientific reports
January 1, 1970
Chen Hua et al. (8 authors)
Journal ArticleSystematic ReviewMeta-AnalysisHuman Study
Study Details

Study Goal

The researchers aimed to compare the effectiveness of different cardiac rehabilitation interventions, including High-Intensity Interval Training (HIIT), in improving outcomes for chronic heart failure patients.

Results Summary

Center-based cardiac rehabilitation with HIIT was the most effective in enhancing left ventricular ejection fraction (LVEF). Combined CR with aerobic and resistance training improved quality of life, exercise capacity, and reduced rehospitalization rates.

Population

Chronic heart failure (CHF) patients

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
All interventions
increase
routine care
-
-
outperformed
#1
Combined CR with aerobic exercise and resistance training (HCR [AE + RE])
increase
Minnesota Living with Heart Failure Questionnaire (MLHFQ) scores
-
-
significantly improved
#2
Combined CR with aerobic exercise and resistance training (HCR [AE + RE])
increase
6-min walk test (6MWT) performance
-
-
significantly improved
#3
Combined CR with aerobic exercise and resistance training (HCR [AE + RE])
decrease
rehospitalization rates
-
-
reduced
#4
Center-based cardiac rehabilitation (CBCR) with high-intensity interval training (HIIT)
increase
left ventricular ejection fraction (LVEF)
-
-
was the most effective in enhancing
#5
CBCR(AE)
increase
peak oxygen uptake (Peak VO2)
-
-
demonstrated the greatest improvement in
#6
Abstract

Chronic heart failure (CHF) represents one of the most severe and advanced stages of cardiovascular disease. Despite the critical importance of cardiac rehabilitation (CR) in CHF management, while studies have explored the effectiveness of various CR delivery modes and offered valuable context-specific insights, their relative efficacy remains inconsistent across different patient groups, healthcare environments, and intervention approaches. A clearer understanding requires comprehensive comparisons and in-depth analyses to address these variations. Systematic searches were conducted in databases including Pubmed, Embase, Cochrane Central Register of Controlled Trials, and Web of Science, up to August 2024. Two researchers independently screened the literature according to strict inclusion criteria, extracted relevant data, and assessed the quality of included studies using Cochrane Collaboration tools and the Jadad scale. Subsequent pairwise and network meta-analyses were performed using statistical software, including Stata 17.0, to present the results graphically. The network meta-analysis included 9,552 articles, with 33 meeting the inclusion criteria and examining eleven different interventions. All interventions outperformed routine care. Combined CR with aerobic exercise and resistance training (HCR [AE + RE]) significantly improved Minnesota Living with Heart Failure Questionnaire (MLHFQ) scores and 6-min walk test (6MWT) performance, and reduced rehospitalization rates [SUCRA = 96%]. Center-based cardiac rehabilitation (CBCR) with high-intensity interval training (HIIT) was the most effective in enhancing left ventricular ejection fraction (LVEF), while CBCR(AE) demonstrated the greatest improvement in peak oxygen uptake (Peak VO

Medical Subject Headings (MeSH)
HumansHeart FailureCardiac RehabilitationNetwork Meta-AnalysisExercise TherapyChronic DiseaseQuality of LifeExerciseTreatment OutcomeResistance Training
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality90/10
Citation Metrics
Total Citations1
Citations/Year1.0
Research Impact Scores
APT Score0.50
Weight Score1.54
Normalized Score0.72
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