Panacea Index Logo

Command Palette

Search for a command to run...

Adherence to MIND Diet and Risk of Recurrent Depressive Symptoms: Prospective Whitehall II Cohort Study.

Nutrients
November 26, 2024
Husnain Arshad et al. (7 authors)
Journal ArticleHuman Study
Study Details

Study Goal

The researchers aimed to examine the association between adherence to the MIND diet and its components with recurrent depressive symptoms in a British cohort.

Results Summary

Higher adherence to the MIND diet was associated with a 26% lower odds of recurrent depressive symptoms, with green leafy vegetables, other vegetables, and berries showing independent protective effects.

Population

4824 participants (73% men, mean age 61) from the British Whitehall II cohort study.

Effective Dosage

Not specified

Duration

13 years of follow-up

Interactions

None mentioned

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
higher adherence to the MIND diet
decrease
recurrent depressive symptoms
participants from the British Whitehall II cohort study
26%
had 26% lower odds of experiencing
#1
green leafy vegetables
decrease
recurrent depressive symptoms
participants from the British Whitehall II cohort study
OR = 0.59, 95% CI: 0.45-0.78
independent associations were observed for
#2
other vegetables
decrease
recurrent depressive symptoms
participants from the British Whitehall II cohort study
OR = 0.43, 95% CI:0.24-0.77
independent associations were observed for
#3
berries
decrease
recurrent depressive symptoms
participants from the British Whitehall II cohort study
OR = 0.74, 95% CI: 0.61-0.89
independent associations were observed for
#4
Abstract

BACKGROUND/OBJECTIVES: This study examined the association between adherence to the Mediterranean dietary approaches to stop hypertension Intervention for Neurodegenerative Delay (MIND) diet, its components, and recurrent depressive symptoms (DepSs). METHODS: The analyses included 4824 participants (73% men, mean age = 61; SD = 5.9) from the British Whitehall II cohort study. The MIND diet scores were derived from a validated 127-item food frequency questionnaire in 2002-2004. DepSs were assessed by the Center for Epidemiologic Studies Depression Scale (score ≥ 16) or by use of antidepressant drugs, and recurrence was defined as having DepSs in at least two of the four repeated measurements in the 2002-2004, 2007-2009, 2012-2013, and 2015-2016 follow-up phases. RESULTS: Recurrent DepSs were observed in 13.3% of the participants over 13 years of follow-up. After adjusting for potential confounders, participants in the highest tertile of the MIND diet score (where a higher score represents a higher diet quality) had 26% lower odds of experiencing recurrent DepSs (OR = 0.74; 95% CI 0.58-0.93) compared to those in the lowest tertile. In mutually adjusted analyses of 14 MIND diet components in relation to recurrent DepSs, independent associations were observed for green leafy vegetables (OR = 0.59, 95% CI: 0.45-0.78), other vegetables (OR = 0.43, 95% CI:0.24-0.77), and berries (OR = 0.74, 95% CI: 0.61-0.89). CONCLUSIONS: In this British prospective cohort, good adherence to the MIND diet, particularly to the recommendations for vegetables and berries, was associated with a lower risk of recurrent depressive symptoms, independent of socio-economic, health behavior, and health status factors, including baseline cognitive impairment and antecedents of DepSs.

Medical Subject Headings (MeSH)
HumansMaleFemaleMiddle AgedDiet, MediterraneanProspective StudiesDepressionDietary Approaches To Stop HypertensionRecurrenceAgedRisk FactorsPatient Compliance
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality88/10
Citation Metrics
Total Citations2
Citations/Year2.0
Research Impact Scores
APT Score0.25
Weight Score2.87
Normalized Score0.72
Related Supplements
Adherence to MIND Diet and Risk of Recurrent Depressive Symp... | Panacea Index