Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults <50 Years of Age: A Systematic Review and Meta-Analysis.
Study Goal
The researchers aimed to determine how variables like age and training duration affect the efficacy of creatine supplementation combined with resistance training for improving muscle strength.
Results Summary
Creatine supplementation combined with resistance training significantly increased upper-body strength compared to a placebo, with a weighted mean difference of 4.43 kg. The study included 23 studies but did not fully detail the impact of confounding variables.
Population
Primarily males (447 participants), with some females (49 participants).
Effective Dosage
Not specified in the abstract.
Duration
Not specified in the abstract.
Interactions
None mentioned.
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
creatine supplementation combined with resistance training | increase | upper-body muscle strength | - | WMD = 4.43 kg | significantly increased | #1 |
BACKGROUND: Numerous meta-analyses have assessed the efficacy of creatine supplementation in increasing muscle strength. However, most have not considered the effect of the participants' age, training duration, or other confounding variables on strength outcomes. Therefore, the purpose of this study was to consider the effect of these variables on the potential efficacy of creatine supplementation and resistance training for improving measures of muscle strength. METHODS: Four databases were searched (MEDLINE, Scopus, Embase, and SPORTDiscus) with a search end date of 22 May 2024. Twenty-three studies were included, with 20 studies involving males (447 male participants), 2 studies involving females (40 female participants), and 1 study involving both males and females (13 male participants and 9 female participants). RESULTS: In comparison with a placebo, creatine supplementation combined with resistance training significantly increased upper-body (WMD = 4.43 kg,