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Impact of Dance or Music and Meditation on the Progression of Parkinson Disease With Mild or Moderate Severity: Protocol for a Pilot Randomized Controlled Trial.

JMIR research protocols
October 29, 2024
Bhagyashree Mehrotra et al. (9 authors)
Journal ArticleClinical Trial ProtocolHuman StudyClinical
Study Details

Study Goal

The researchers aimed to evaluate the effectiveness of dance or music combined with meditation on Parkinson's disease progression, cognitive functions, mood, behavior, and caregiver burden.

Results Summary

Data collection was completed with 28 participants, but results are pending analysis and expected to be published in December 2024. The study anticipates insights into improving quality of life and slowing PD progression through these interventions.

Population

30 patients with mild to moderate Parkinson's disease in Mumbai, India, excluding those with advanced PD, severe balance issues, age >80 years, or other movement disorders.

Effective Dosage

Guided meditation sessions thrice weekly (frequency specified, exact duration per session not mentioned).

Duration

6 months

Interactions

None mentioned

Extracted Claims (3)
InterventionDirectionEndpointPopulationDosageImpactClaim #
dance or music sessions and guided meditation
increase
symptoms and quality of life
patients with PD
-
improve
#1
dance or music sessions and guided meditation
increase
quality of life
patients with PD
-
improving
#2
dance or music sessions and guided meditation
decrease
progression of PD
patients with PD
-
slowing
#3
Abstract

BACKGROUND: Parkinson disease (PD) is a progressive neurodegenerative disorder characterized by motor dysfunctions and nonmotor symptoms. Current treatments do not alter disease progression, highlighting the need for alternative therapies. Music, dance, and mindfulness meditation have shown the potential to improve symptoms and quality of life in patients with PD. OBJECTIVE: This study aims to evaluate the effectiveness of dance or music and meditation on PD progression, cognitive functions, mood, behavior, and caregiver burden. METHODS: This study is a single-blinded, longitudinal, parallel, randomized controlled trial. The participants consist of 30 patients with mild to moderate PD residing in Mumbai, India, who can physically participate in the activities. The exclusion criteria include advanced PD, severe balance issues, age >80 years, and other movement disorders. Participants in the intervention group will engage in dance or music sessions and guided meditation thrice weekly for 6 months. The control group will continue their usual activities and medication. The primary outcome is the progression of PD symptoms, measured using the Unified Parkinson's Disease Rating Scale I-III, and quality of life, measured using the Parkinson's Disease Questionnaire-39. The secondary outcomes include cognitive functions (Mini-Mental State Examination), mood (Beck Depression Inventory and Parkinson Anxiety Scale), mobility (timed up and go and Berg Balance Test), behavioral disorders (Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease Rating Scale), and caregiver burden (Zarit Burden Interview and Parkinson's Disease Questionnaire-Carer). RESULTS: Data collection was completed in February 2024, with 28 participants finishing the study (intervention group: n=15, 54% and control group: n=13, 46%). Data analysis is underway, with results expected to be published in December 2024. CONCLUSIONS: This study aims to provide significant insights into the effectiveness of dance or music and meditation in improving the quality of life and slowing the progression of PD. The findings are anticipated to support using these nonpharmaceutical therapies as complementary approaches to managing PD. TRIAL REGISTRATION: CTRI/2023/03/051064; https://tinyurl.com/2xdus53j. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/59018.

Medical Subject Headings (MeSH)
HumansParkinson DiseaseMeditationDisease ProgressionPilot ProjectsMusic TherapySingle-Blind MethodMaleFemaleDance TherapyQuality of LifeAgedMiddle AgedSeverity of Illness IndexIndiaDancingLongitudinal StudiesRandomized Controlled Trials as Topic
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality85/10
Citation Metrics
Total Citations1
Citations/Year1.0
Research Impact Scores
APT Score0.50
Weight Score2.70
Normalized Score0.67
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