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The Effect of Synbiotics and Probiotics on Ochratoxin Concentrations in Blood and Tissues, Health Status, and Gastrointestinal Function in Turkeys Fed Diets Contaminated with Ochratoxin A.

Animals : an open access journal from MDPI
October 18, 2024
Magdalena Mazur-Kuśnirek et al. (4 authors)
Journal ArticleAnimal Study
Study Details

Study Goal

The researchers aimed to evaluate the effects of synbiotic preparations on carcass quality, gastrointestinal functional status, ochratoxin A accumulation, and health status in turkeys fed OTA-contaminated diets compared to commercial probiotic additives.

Results Summary

Synbiotics reduced digesta pH in certain digestive tract sections, significantly decreased liver weight at weeks 6 and 15, and improved health status while reducing mycotoxin accumulation in organs and tissues. No significant differences were found in growth performance or carcass quality.

Population

120 female BIG 6 turkeys divided into six treatment groups.

Effective Dosage

0.5 g/kg of synbiotics S1, S2, or S3.

Duration

Weeks 6 and 15 (specific total duration not stated).

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
OTA-contaminated diet without additives
no change
growth performance
female BIG 6 turkeys
no significant differences
no significant differences
#1
OTA-contaminated diet without additives
no change
carcass quality
female BIG 6 turkeys
no significant differences
no significant differences
#2
probiotics or synbiotics
decrease
pH of the digesta in certain sections of the turkey digestive tract
female BIG 6 turkeys
-
resulted in a reduced
#3
tested synbiotic additives
decrease
liver weight
female BIG 6 turkeys
-
significantly reduced
#4
probiotic and synbiotic preparations based on lactic acid bacteria strains, inulin, and S. cerevisiae yeasts
increase
health status
turkeys
-
may improve
#5
probiotic and synbiotic preparations based on lactic acid bacteria strains, inulin, and S. cerevisiae yeasts
decrease
mycotoxin accumulation in organs and tissues
poultry
-
reduce
#6
Abstract

The aim of this study was to evaluate carcass quality and analyze gastrointestinal functional status, ochratoxin A (OTA) accumulation in tissues and organs, and the health status of turkeys fed diets contaminated with OTA and supplemented with synbiotic preparations in comparison with commercial probiotic feed additives. The research involved 120 female BIG 6 turkeys, divided into six treatment groups (five replicates, four birds per replicate). Wheat naturally contaminated with OTA (662.03 μg/kg) was used in turkey diets. Turkeys in group 1 received an OTA-contaminated diet without additives. Groups 2 and 3 received 0.4 g/kg of probiotic preparation BioPlus 2B or Cylactin. Groups 4, 5, and 6 received 0.5 g/kg of synbiotics S1, S2, or S3. The following parameters were monitored: growth performance, carcass quality, gastrointestinal tract structure and digesta pH, health status, and concentrations of OTA in the blood and tissues of turkeys. The study found no significant differences in the growth performance and carcass quality of turkey. However, the introduction of probiotics or synbiotics into OTA-contaminated feed mixtures resulted in a reduced pH of the digesta in certain sections of the turkey digestive tract (p < 0.05). Additionally, the tested synbiotic additives significantly reduced liver weight in turkeys at weeks 6 and 15 (p < 0.05). The addition of probiotic and synbiotic preparations based on lactic acid bacteria strains, inulin, and S. cerevisiae yeasts to OTA-contaminated diets in commercial turkey farming may improve health status (p < 0.05) and reduce mycotoxin accumulation in organs and tissues of poultry (p < 0.05).

Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality80/10
Research Impact Scores
APT Score0.05
Weight Score1.22
Normalized Score0.66
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