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Acute caffeine supplementation offsets the impairment in 10-km running performance following one night of partial sleep deprivation: a randomized controlled crossover trial.

European journal of applied physiology
March 1, 2025
Yi-Shan Tsai et al. (9 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine whether acute caffeine supplementation could counteract the negative effects of one-night partial sleep deprivation on endurance exercise performance in recreational runners.

Results Summary

Caffeine improved 10-km running performance by 7.7% after partial sleep deprivation and by 2.8% after normal sleep, effectively offsetting the performance decline caused by sleep deprivation. Performance with caffeine after sleep deprivation was comparable to performance with placebo after normal sleep.

Population

Ten healthy recreational male runners (age 27 ± 6 years).

Effective Dosage

Not specified in the abstract.

Duration

Acute (single-dose) intervention.

Interactions

None mentioned.

Extracted Claims (9)
InterventionDirectionEndpointPopulationDosageImpactClaim #
partial sleep deprivation
decrease
TT performance
ten healthy recreational male runners
5%
resulted in compromised
#1
caffeine
increase
TT performance
ten healthy recreational male runners
7.7%
improved
#2
caffeine
increase
TT performance
ten healthy recreational male runners
2.8%
improved
#3
caffeine
increase
blood glucose concentrations at post-exercise
ten healthy recreational male runners
-
were higher
#4
caffeine
increase
lactate concentrations at post-exercise
ten healthy recreational male runners
-
were higher
#5
caffeine
increase
glycerol concentrations at post-exercise
ten healthy recreational male runners
-
were higher
#6
caffeine
increase
heart rate during TT
ten healthy recreational male runners
-
were higher
#7
caffeine
increase
speed/RPE ratio during TT
ten healthy recreational male runners
-
were higher
#8
caffeine supplementation
increase
10-km running performance
ten healthy recreational male runners
-
offsets the negative effects
#9
Abstract

INTRODUCTION: Whether acute caffeine supplementation can offset the negative effects of one-night of partial sleep deprivation (PSD) on endurance exercise performance is currently unknown. METHODS: Ten healthy recreational male runners (age: 27 ± 6 years; RESULTS: PSD resulted in compromised TT performance compared to NS in the placebo conditions by 5% (51.9 ± 7.7 vs. 49.4 ± 6.9 min, p = 0.001). Caffeine improved TT performance compared to placebo following both PSD by 7.7% (PSD-Caf: 47.9 ± 7.3 min vs. PSD-Pla: 51.9 ± 7.7 min, p = 0.007) and NS by 2.8% (NS-Caf: 48.0 ± 6.4 min vs. NS-Pla: 49.4 ± 6.9 min, p = 0.049). TT performance following PSD-Caf was not different from either NS-Pla or NS-Caf (p = 0.185 and p = 0.891, respectively). Blood glucose, lactate, and glycerol concentrations at post-exercise, as well as heart rate and the speed/RPE ratio during TT, were higher in caffeine trials compared to placebo. CONCLUSIONS: Caffeine supplementation offsets the negative effects of one-night PSD on 10-km running performance.

Medical Subject Headings (MeSH)
HumansCaffeineMaleRunningAdultSleep DeprivationCross-Over StudiesAthletic PerformanceDietary SupplementsPhysical EnduranceLactic AcidCentral Nervous System StimulantsBlood Glucose
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality78/10
Research Impact Scores
APT Score0.05
Weight Score2.56
Normalized Score0.70
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