Neuro- and immuno-modulation mediated by the cardiac sympathetic nerve: a novel insight into the anti-ischemic efficacy of acupuncture.
Study Goal
The researchers aimed to review the role of sympathetic tone in adverse left ventricular remodeling post-myocardial ischemia and explore acupuncture's potential to improve cardiac function and mitigate these effects.
Results Summary
The abstract suggests acupuncture effectively improves cardiac function, eliminates arrhythmia, and mitigates adverse left ventricular remodeling, though specific data or statistical significance are not provided.
Population
Patients with myocardial ischemia and adverse left ventricular remodeling (not further specified).
Effective Dosage
Not available
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Acupuncture | increase | cardiac function | - | - | effectively improve | #1 |
Acupuncture | decrease | arrhythmia | - | - | eliminate | #2 |
Acupuncture | decrease | adverse LV remodeling | - | - | mitigate | #3 |
Communication between sympathetic nerves and the immune system is a crucial and active process during myocardial ischemia (MI), as myocardial damage and inflammatory stimuli concurrently occur. Sympathetic nerves undergo structural and functional changes after MI, leading to adverse left ventricular (LV) remodeling and heart failure (HF). The complex inflammatory response to MI, including local myocardial anti-inflammatory repair and systemic immune reactions, plays a key role in adverse LV remodeling. Here, we review the progressive structural and electrophysiological remodeling of the LV and the involvement of sympathetic tone in complex and dynamic processes that are susceptible to MI pathological conditions. Acupuncture has been reported to effectively improve cardiac function, eliminate arrhythmia, and mitigate adverse LV remodeling