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Analysis of combinatory effects of free weight resistance training and a high-protein diet on body composition and strength capacity in postmenopausal women - A 12-week randomized controlled trial.

The journal of nutrition, health & aging
October 1, 2024
Paulina Ioannidou et al. (6 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine the effects of resistance training (RT) and a high-protein diet (HPD) on body composition, muscle thickness, and strength capacity in postmenopausal women.

Results Summary

RT significantly increased skeletal muscle mass, reduced fat mass in one group, and improved muscle thickness and strength (grip strength, squat, and deadlift). HPD alone had minimal effects on strength but no impact on body composition.

Population

Healthy postmenopausal women (age 58.2 ± 5.6 years).

Effective Dosage

RT: 3 sessions/week, 5 exercises each; HPD: 2.5 g/kg fat-free mass.

Duration

12 weeks.

Interactions

None mentioned.

Extracted Claims (13)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Resistance training (RT)
increase
skeletal muscle mass (SMM)
postmenopausal women
Δ+1.4 ± 0.9 kg (TP group); Δ+1.2 ± 1.3 kg (T group)
significantly increased
#1
Resistance training (RT) (T group only)
decrease
fat mass (FM)
postmenopausal women
Δ-2.4 ± 2.9 kg
reduced
#2
Resistance training (RT)
increase
muscle thickness of the M. biceps brachii
postmenopausal women
Δ+0.4 ± 0.3 cm (TP group); Δ+0.3 ± 0.3 cm (T group)
significant increase
#3
Resistance training (RT) + high-protein diet (HPD) (TP group only)
increase
muscle thickness of the M. biceps femoris
postmenopausal women
Δ+0.3 ± 0.4 cm
significant increase
#4
High-protein diet (HPD) without training
no change
body composition
postmenopausal women
-
does not affect
#5
Resistance training (RT)
increase
grip strength
postmenopausal women
Δ+4.7 ± 2.4 kg (TP group); Δ+3.6 ± 3.0 kg (T group)
significant increase
#6
Resistance training (RT)
increase
1-RM in the squat (BBS)
postmenopausal women
Δ+30.0 ± 14.2 kg (TP group); Δ+34.0 ± 12.0 kg (T group)
significant increase
#7
Resistance training (RT)
increase
1-RM in the deadlift (DL)
postmenopausal women
Δ+20.8 ± 10.3 kg (TP group); Δ+22.1 ± 7.6 kg (T group)
significant increase
#8
High-protein diet (HPD) without training (CP group)
increase
1-RM in the squat (BBS)
postmenopausal women
Δ+7.5 ± 5.4 kg
significant increase
#9
High-protein diet (HPD) without training (CP group)
increase
1-RM in the deadlift (DL)
postmenopausal women
Δ+5.5 ± 7.7 kg
significant increase
#10
Resistance training (RT)
increase
body composition and strength capacity
postmenopausal women
-
enhances
#11
High-protein diet (HPD) without training
increase
BBS and DL
postmenopausal women
-
has a trivial significant effect
#12
High-protein diet (HPD) with resistance training (RT)
no change
body composition and strength capacity
postmenopausal women
-
has no clear additive effect
#13
Abstract

BACKGROUND: Menopause has a significant impact on the endocrine system of middle-aged women, resulting in a loss of skeletal muscle mass (SMM), changes in fat mass (FM) and a reduction in strength capacity. Resistance training (RT) and a high-protein diet (HPD) are effective methods for maintaining or increasing SMM. This study aims to determine the effects of HPD and RT on body composition, muscle thickness and strength capacity in postmenopausal women. METHODS: In total 55 healthy postmenopausal women (age: 58.2 ± 5.6 years, weight 69.1 ± 9.6 kg, height 166.5 ± 6.5 cm) successfully participated in the study. The women were randomly assigned to either group: training + protein (2.5 g/kg fat-free mass (FFM)) (n = 15; TP); only training (n = 12; T); only protein (2.5 g/kg FFM) (n = 14; CP) or control (n = 14; C). TP and T performed RT for 12 weeks with three training sessions and five exercises each. CP and C were prohibited from training during the period. The main parameters analysed for body composition were FFM, SMM, FM, muscle thickness of the M. rectus femoris, M. biceps femoris, M. triceps brachii and M. biceps brachii muscles. Strength was tested using a dynamometer for grip strength and 1-RM in the squat (BBS) and deadlift (DL). RESULTS: The SMM significantly increased by RT (TP: (Δ+1.4 ± 0.9 kg; p < 0.05; d = 0.4; T: Δ+1.2 ± 1.3kg; p < 0.05; d = 0.3) and FM could be reduced only in T: (Δ-2.4 ± 2.9 kg; p < 0.05; d = 0.3). In muscle thickness a significant increase in the M. biceps brachii in both training groups (TP: (Δ+0.4 ± 0.3 cm; p < 0.05; d = 1.6; T: (Δ+0.3 ± 0.3 cm; p < 0.05; d = 0.9) and in M. biceps femoris only in TP (Δ+0.3 ± 0.4 cm; p < 0.05; d = 0.9) were observed. HPD without training does not affect body composition, A significant increase in grip strength (TP: Δ+4.7 ± 2.4 kg; (p < 0.05; d = 1.5; T: (Δ+3.6 ± 3.0 kg; p < 0.05; d = 0.8), in BBS (TP: (Δ+30.0 ± 14.2 kg; p < 0.05; d = 1.5; T: (Δ+34.0 ± 12.0 kg; p < 0.05; d = 2.4) and in DL (TP: (Δ+20.8 ± 10.3 kg; p < 0.05; d = 1.6; T: (Δ+22.1 ± 7.6 kg; p < 0.05; d = 2.0) was observed in both training groups. The CP also recorded a significant increase in the BBS (Δ+7.5 ± 5.4 kg; p < 0.05; d = 0.4) and in DL (Δ+5.5 ± 7.7 kg; p < 0.05; d = 0.5). No significant differences were detected for TP and T for any of the parameters. CONCLUSION: The results indicate that RT enhances body composition and strength capacity in postmenopausal women and is a preventive strategy against muscle atrophy. Besides HPD without training has a trivial significant effect on BBS and DL. HPD with RT has no clear additive effect on body composition and strength capacity. Further studies are needed to confirm these observations.

Medical Subject Headings (MeSH)
HumansFemaleResistance TrainingPostmenopauseBody CompositionMiddle AgedMuscle StrengthDiet, High-ProteinMuscle, Skeletal
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality80/10
Research Impact Scores
APT Score0.05
Weight Score2.43
Normalized Score0.70
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