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Vitamin D deficiency: A forgotten aspect in sleep disorders? A critical update.

Sleep medicine
September 1, 2024
Sophia Schiza et al. (5 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to review the current evidence on the association between Vitamin D and sleep disorders, including OSA, in adults and children.

Results Summary

The study found a notable link between OSA and decreased serum Vitamin D levels, with worsening deficiency as OSA severity increased. Vitamin D supplementation may optimize sleep quality, but causality between low Vitamin D and OSA remains unclear.

Population

Adults and children with sleep disorders, particularly OSA.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (5)
InterventionDirectionEndpointPopulationDosageImpactClaim #
-
decrease
serum Vitamin D levels
patients with Obstructive sleep apnoea (OSA)
-
a notable link has been identified
#1
-
decrease
decrease in serum Vitamin D levels
patients with worsening severity of sleep apnea
-
appears to intensify
#2
Vitamin D
neutral
cardiometabolic morbidity
patients with OSA
-
could also potentially serve as a mediator or provide an explanation for the association
#3
supplementation of Vitamin D
increase
sleep quality
-
-
can optimize
#4
-
neutral
sleep disorders and Vitamin D levels
children and adolescents
-
a link
#5
Abstract

Over the past few years, there has been a surge in interest regarding the connection between sleep duration and quality, sleep disorders, mainly Obstructive sleep apnoea (OSA) and Vitamin D. There is growing evidence to support a new role of Vitamin D in the maintenance and regulation of optimal sleep. Furthermore, a notable link has been identified between OSA and a decrease in serum Vitamin D levels, which appears to intensify as the severity of sleep apnea worsens. Vitamin D status could also potentially serve as a mediator or provide an explanation for the association between OSA and cardiometabolic morbidity, but the current state of research in this area is inadequate. Studies have indicated that the supplementation of Vitamin D can optimize sleep quality, presenting more proof of the connection between insufficient vitamin D levels and sleep disorders. However, it is unclear whether low serum Vitamin D levels are a contributing factor to OSA development or if OSA predisposes individuals to Vitamin D deficiency. As a result, various studies have endeavored to examine the complex relationship between OSA and Vitamin D deficiency. In children and adolescents, while data is limited, there seems also to be a link between sleep disorders and Vitamin D levels. Therefore, the objective of this review is to provide a comprehensive overview of the current evidence on the association between Vitamin D and sleep disorders in both adults and children.

Medical Subject Headings (MeSH)
HumansVitamin D DeficiencyVitamin DSleep Apnea, ObstructiveSleep Wake DisordersDietary Supplements
Study Links
Quality Scores
SafetyNot Assessed
Efficacy70/10
Quality65/10
Citation Metrics
Total Citations6
Citations/Year6.0
Relative Citation Ratio2.78
Research Impact Scores
APT Score0.95
Weight Score2.57
Normalized Score0.61
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