Vitamin D deficiency: A forgotten aspect in sleep disorders? A critical update.
Study Goal
The researchers aimed to review the current evidence on the association between Vitamin D and sleep disorders, including OSA, in adults and children.
Results Summary
The study found a notable link between OSA and decreased serum Vitamin D levels, with worsening deficiency as OSA severity increased. Vitamin D supplementation may optimize sleep quality, but causality between low Vitamin D and OSA remains unclear.
Population
Adults and children with sleep disorders, particularly OSA.
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
- | decrease | serum Vitamin D levels | patients with Obstructive sleep apnoea (OSA) | - | a notable link has been identified | #1 |
- | decrease | decrease in serum Vitamin D levels | patients with worsening severity of sleep apnea | - | appears to intensify | #2 |
Vitamin D | neutral | cardiometabolic morbidity | patients with OSA | - | could also potentially serve as a mediator or provide an explanation for the association | #3 |
supplementation of Vitamin D | increase | sleep quality | - | - | can optimize | #4 |
- | neutral | sleep disorders and Vitamin D levels | children and adolescents | - | a link | #5 |
Over the past few years, there has been a surge in interest regarding the connection between sleep duration and quality, sleep disorders, mainly Obstructive sleep apnoea (OSA) and Vitamin D. There is growing evidence to support a new role of Vitamin D in the maintenance and regulation of optimal sleep. Furthermore, a notable link has been identified between OSA and a decrease in serum Vitamin D levels, which appears to intensify as the severity of sleep apnea worsens. Vitamin D status could also potentially serve as a mediator or provide an explanation for the association between OSA and cardiometabolic morbidity, but the current state of research in this area is inadequate. Studies have indicated that the supplementation of Vitamin D can optimize sleep quality, presenting more proof of the connection between insufficient vitamin D levels and sleep disorders. However, it is unclear whether low serum Vitamin D levels are a contributing factor to OSA development or if OSA predisposes individuals to Vitamin D deficiency. As a result, various studies have endeavored to examine the complex relationship between OSA and Vitamin D deficiency. In children and adolescents, while data is limited, there seems also to be a link between sleep disorders and Vitamin D levels. Therefore, the objective of this review is to provide a comprehensive overview of the current evidence on the association between Vitamin D and sleep disorders in both adults and children.