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Layperson-Delivered Telephone-Based Behavioral Activation Among Low-Income Older Adults During the COVID-19 Pandemic: The HEAL-HOA Randomized Clinical Trial.

JAMA network open
January 1, 1970
Jojo Yan Yan Kwok et al. (7 authors)
Journal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to compare the effects of telephone-based mindfulness interventions versus befriending on loneliness among at-risk older adults.

Results Summary

The mindfulness group showed significant reductions in loneliness measured by both the UCLA Loneliness Scale and the De Jong Gierveld Loneliness Scale at 3 months compared to befriending, though perceived stress increased. Sleep quality improved, but no significant differences were observed in depression, life satisfaction, or social network.

Population

Chinese older adults (≥65 years) who were lonely, digitally excluded, living alone, and below the poverty line.

Effective Dosage

Twice-weekly 30-minute telephone sessions for 4 weeks.

Duration

4 weeks

Interactions

None mentioned

Extracted Claims (16)
InterventionDirectionEndpointPopulationDosageImpactClaim #
telephone-based behavioral activation
decrease
loneliness measured by the UCLA Loneliness Scale
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
mean difference -1.96 points
significantly reduced
#1
telephone-based mindfulness
decrease
loneliness measured by the UCLA Loneliness Scale
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
mean difference -1.49 points
significantly reduced
#2
telephone-based behavioral activation
no change
loneliness measured by the De Jong Gierveld Loneliness Scale
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
mean difference -0.06 points
was not significantly reduced
#3
telephone-based mindfulness
decrease
loneliness measured by the De Jong Gierveld Loneliness Scale
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
mean difference 0.22 points
was significantly reduced
#4
telephone-based behavioral activation
increase
sleep quality
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
-
improved
#5
telephone-based mindfulness
increase
sleep quality
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
-
improved
#6
telephone-based behavioral activation
increase
perceived stress
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
-
increased
#7
telephone-based mindfulness
increase
perceived stress
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
-
increased
#8
telephone-based behavioral activation
increase
psychological well-being
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
-
improved
#9
telephone-based behavioral activation
increase
perceived social support
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
-
improved
#10
telephone-based behavioral activation
no change
depression
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
-
no statistically significant between-group differences were observed
#11
telephone-based mindfulness
no change
depression
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
-
no statistically significant between-group differences were observed
#12
telephone-based behavioral activation
no change
life satisfaction
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
-
no statistically significant between-group differences were observed
#13
telephone-based mindfulness
no change
life satisfaction
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
-
no statistically significant between-group differences were observed
#14
telephone-based behavioral activation
no change
social network
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
-
no statistically significant between-group differences were observed
#15
telephone-based mindfulness
no change
social network
at-risk older adults (≥65 years, lonely, digitally excluded, living alone, living below the poverty line)
-
no statistically significant between-group differences were observed
#16
Abstract

IMPORTANCE: Older adults are particularly vulnerable to loneliness and its physical and psychosocial sequelae, but scalable interventions are lacking, especially during disasters such as pandemics. OBJECTIVE: To compare the effects of layperson-delivered, telephone-based behavioral activation and mindfulness interventions vs telephone-based befriending on loneliness among at-risk older adults. DESIGN, SETTING, AND PARTICIPANTS: This assessor-blinded, 3-arm randomized clinical trial screened Chinese older adults through household visits and community referrals from April 1, 2021, to April 30, 2023, in Hong Kong. Eligible participants (≥65 years of age) who were lonely, digitally excluded, living alone, and living below the poverty line and provided consent to participate were randomized into behavioral activation, mindfulness, and befriending groups. Assessments were conducted at baseline, 1 month, and 3 months. INTERVENTION: As part of the Helping Alleviate Loneliness in Hong Kong Older Adults (HEAL-HOA) dual randomized clinical trial, 148 older laypersons were trained to deliver a twice-weekly 30-minute intervention via telephone for 4 weeks. MAIN OUTCOMES AND MEASURES: The primary outcome was loneliness measured by the UCLA Loneliness Scale (range, 20-80) and the De Jong Gierveld Loneliness Scale (range, 0-6), with higher scores on both scales indicating greater loneliness. Secondary outcomes were depression, perceived stress, life satisfaction, psychological well-being, sleep quality, perceived social support, and social network. RESULTS: A total of 1151 participants (mean [SD] age, 76.6 [7.8] years; 843 [73.2%] female) were randomized to the behavioral activation (n = 335), mindfulness (n = 460) or befriending (n = 356) group. Most were widowed or divorced (932 [81.0%]), had primary education or below (782 [67.9%]), and had 3 or more chronic diseases (505 [43.9%]). Following intention-to-treat principles, linear mixed-effects regression model analyses showed that loneliness measured by the UCLA Loneliness Scale was significantly reduced in the behavioral activation group (mean difference [MD], -1.96 [95% CI, -3.16 to -0.77] points; P < .001]) and in the mindfulness group (MD, -1.49 [95% CI, -2.60 to -0.37] points; P = .004) at 3 months compared with befriending. Loneliness measured by the De Jong Gierveld Loneliness Scale was not significantly reduced at 3 months in the behavioral activation group (MD, -0.06 [95% CI, -0.26 to 0.13] points; P > .99]) but was in the mindfulness group (MD, 0.22 [95% CI, 0.03 to 0.40] points; P = .01) at 3 months compared with befriending. In the behavioral activation and mindfulness groups, sleep quality improved compared with befriending, but perceived stress increased. Psychological well-being and perceived social support improved in the behavioral activation group. No statistically significant between-group differences were observed in depression, life satisfaction, or social network. CONCLUSION AND RELEVANCE: In this randomized clinical trial, scalable psychosocial interventions delivered remotely by older laypersons appeared promising in reducing later life loneliness and addressing the pressing mental health challenges faced by aging populations and professional geriatric mental health workforce shortages. Further research should explore ways to maximize the clinical relevance and cost-effectiveness of these interventions. TRIAL REGISTRATION: Chinese Clinical Trial Registry Identifier: ChiCTR2300072909.

Medical Subject Headings (MeSH)
HumansCOVID-19FemaleAgedMaleLonelinessHong KongTelephonePovertyMindfulnessSARS-CoV-2PandemicsAged, 80 and over
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality85/10
Citation Metrics
Total Citations4
Citations/Year4.0
Research Impact Scores
APT Score0.75
Weight Score1.61
Normalized Score0.67
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