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Comparing the effects of different acupoint-stimulating therapies in mitigating post-stroke spasticity and motor dysfunction in older stroke survivors: A network meta-analysis of randomized trials.

Maturitas
September 1, 2024
Guan-Cheng Zhu et al. (3 authors)
Journal ArticleMeta-AnalysisSystematic ReviewComparative StudyReviewHuman Study
Study Details

Study Goal

The researchers aimed to compare the effects of different acupoint-stimulating therapies (including acupressure) on spasticity and motor dysfunction in older stroke survivors.

Results Summary

Non-invasive electroacupuncture and warm acupuncture were more effective in reducing spasticity than conventional acupuncture and invasive electroacupuncture, while conventional acupuncture and invasive electroacupuncture improved motor function, though with significant inconsistency for invasive electroacupuncture.

Population

Older adults with stroke-related spasticity and motor dysfunction.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
non-invasive electroacupuncture
decrease
spasticity
older stroke survivors
standardized mean difference and 95 % confidence intervals = 1.35/1.19 [0.57; 2.13/0.54; 1.83]
were more effective in reducing
#1
warm acupuncture
decrease
spasticity
older stroke survivors
standardized mean difference and 95 % confidence intervals = 1.35/1.19 [0.57; 2.13/0.54; 1.83]
were more effective in reducing
#2
non-invasive electroacupuncture
decrease
spasticity
older stroke survivors
standardized mean difference and 95 % confidence intervals = 0.96/0.80 [0.12; 1.80/0.08; 1.51]
were more effective in reducing spasticity than
#3
warm acupuncture
decrease
spasticity
older stroke survivors
standardized mean difference and 95 % confidence intervals = 0.96/0.80 [0.12; 1.80/0.08; 1.51]
were more effective in reducing spasticity than
#4
conventional acupuncture
increase
motor function
older stroke survivors
standardized mean difference and 95 % confidence intervals = 0.99/1.41 [0.42; 1.56/0.54; 2.28]
were effective in improving
#5
invasive electroacupuncture
increase
motor function
older stroke survivors
standardized mean difference and 95 % confidence intervals = 0.99/1.41 [0.42; 1.56/0.54; 2.28]
were effective in improving
#6
Abstract

Acupoint-stimulating therapies have often been used to manage stroke-related spasticity and motor dysfunction. However, the effects of different acupoint-stimulating therapies in older stroke survivors have been unclear. This systematic review and network meta-analysis compared the effects of different acupoint-stimulating therapies in managing spasticity and motor dysfunction in older stroke survivors. The study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We searched 7 databases for studies published up to July 2023. Inclusion criteria were: (1) older adults with strokes; (2) treatments were acupoint-stimulating therapies; (3) a control group did not receive acupoint-stimulating therapy, or the study compared different acupoint-stimulating therapies; and (4) outcomes included spasticity and motor function. Methodological quality was assessed with Risk-of-bias tool for randomized trials version 2, while R and Metainsight were used to conduct the network meta-analysis. We analyzed 27 studies and the results showed that non-invasive electroacupuncture and warm acupuncture were more effective in reducing spasticity than conventional acupuncture (standardized mean difference and 95 % confidence intervals = 1.35/1.19 [0.57; 2.13/0.54; 1.83]) and invasive electroacupuncture (standardized mean difference and 95 % confidence intervals = 0.96/0.80 [0.12; 1.80/0.08; 1.51]). Conventional acupuncture and invasive electroacupuncture were effective in improving motor function (standardized mean difference and 95 % confidence intervals = 0.99/1.41 [0.42; 1.56/0.54; 2.28]). However, there was significant inconsistency for the effects of invasive electroacupuncture between studies. Our findings suggest that for older stroke survivors with spasticity, non-invasive electroacupuncture and warm acupuncture are appropriate, whereas conventional acupuncture is more appropriate for patients aiming for motor recovery. SYSTEMATIC REVIEW REGISTRATION: This study was registered in the PROSPERO database (CRD42023442202).

Medical Subject Headings (MeSH)
HumansMuscle SpasticityStrokeRandomized Controlled Trials as TopicAgedAcupuncture TherapyNetwork Meta-AnalysisElectroacupunctureAcupuncture PointsStroke Rehabilitation
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality90/10
Citation Metrics
Total Citations2
Citations/Year2.0
Research Impact Scores
APT Score0.25
Weight Score2.91
Normalized Score0.72
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