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A 12-week double-blind randomised controlled trial investigating the effect of dietary supplementation with 125

The British journal of nutrition
January 1, 1970
Stephanie Watkins et al. (3 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to investigate the effects of daily vitamin D supplementation on underlying inflammation and patient-focused outcomes in adults with asthma.

Results Summary

The abstract does not provide specific results regarding the effects of vitamin D supplementation.

Population

Adults with asthma

Effective Dosage

125 µg daily

Duration

12 weeks

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
-
increase
exacerbation
asthmatics
-
linked to higher rates
#1
-
decrease
lung function
asthmatics
-
linked to reduced
#2
vitamin D supplementation
neutral
-
children with asthma
-
investigating the effect
#3
vitamin D supplementation
neutral
bolus dosing regimens
adults
-
used
#4
vitamin D supplementation
no change
underlying inflammation
adults
-
main outcomes have been patient-focused without investigating
#5
daily 125 µg vitamin D
neutral
-
-
125 µg
administering
#6
Abstract

Vitamin D deficiency has previously been linked to higher rates of exacerbation and reduced lung function in asthmatics. Previous randomised controlled trials investigating the effect of vitamin D supplementation have mainly focused on children with asthma. Trials involving adults have typically used bolus dosing regimens, and the main outcomes have been patient-focused without investigating underlying inflammation. The present study aimed to conduct a 12-week placebo-controlled randomised controlled trials administering a daily 125 µg vitamin D

Medical Subject Headings (MeSH)
HumansAsthmaDouble-Blind MethodDietary SupplementsMaleFemaleAdultVitamin DMiddle AgedVitamin D DeficiencyBiomarkersCholecalciferolLungInterleukin-10Tumor Necrosis Factor-alphaForced Expiratory VolumeYoung Adult
Study Links
Quality Scores
SafetyNot Assessed
Quality75/10
Citation Metrics
Total Citations2
Citations/Year2.0
Research Impact Scores
APT Score0.50
Weight Score1.42
Normalized Score0.55
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