Effects of combined resistance training and Tai Chi on oxidative stress, blood glucose and lipid metabolism and quality of life in elderly patients with type 2 diabetes mellitus.
Study Goal
The researchers aimed to determine the effects of Tai Chi, resistance training, and their combination on oxidative stress, blood glucose, lipid metabolism, and quality of life in elderly patients with type 2 diabetes mellitus.
Results Summary
Tai Chi reduced oxidative stress, improved blood glucose and lipid control, and enhanced quality of life in elderly T2DM patients. The combination intervention further reduced oxidative stress but did not show additional benefits for blood glucose, lipids, or quality of life compared to single interventions.
Population
Elderly patients with type 2 diabetes mellitus (n=24 in Tai Chi group).
Effective Dosage
40 minutes per session, 3 times per week.
Duration
24 weeks.
Interactions
None mentioned.
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
resistance training (RT) | decrease | oxidative stress damage | elderly patients with type 2 diabetes mellitus (T2DM) | - | can reduce | #1 |
Tai Chi (TC) | decrease | oxidative stress damage | elderly patients with type 2 diabetes mellitus (T2DM) | - | can reduce | #2 |
combination intervention (RT & TC) | decrease | oxidative stress damage | elderly patients with type 2 diabetes mellitus (T2DM) | - | can reduce | #3 |
resistance training (RT) | decrease | levels of blood sugar and blood lipid | elderly patients with type 2 diabetes mellitus (T2DM) | - | control | #4 |
Tai Chi (TC) | decrease | levels of blood sugar and blood lipid | elderly patients with type 2 diabetes mellitus (T2DM) | - | control | #5 |
combination intervention (RT & TC) | decrease | levels of blood sugar and blood lipid | elderly patients with type 2 diabetes mellitus (T2DM) | - | control | #6 |
resistance training (RT) | increase | quality of life | elderly patients with type 2 diabetes mellitus (T2DM) | - | improve | #7 |
Tai Chi (TC) | increase | quality of life | elderly patients with type 2 diabetes mellitus (T2DM) | - | improve | #8 |
combination intervention (RT & TC) | increase | quality of life | elderly patients with type 2 diabetes mellitus (T2DM) | - | improve | #9 |
combination intervention (RT & TC) | decrease | level of oxidative stress | elderly patients with type 2 diabetes mellitus (T2DM) | - | can further reduce | #10 |
combination intervention (RT & TC) | no change | blood glucose and lipid control | elderly patients with type 2 diabetes mellitus (T2DM) | - | has no additional benefits | #11 |
combination intervention (RT & TC) | no change | quality of life | elderly patients with type 2 diabetes mellitus (T2DM) | - | has no additional benefits | #12 |
This study examined the effects of resistance training (RT), Tai Chi (TC) and combination intervention (RT & TC) on the oxidative stress, blood glucose and lipid metabolism and quality of life of elderly patients with type 2 diabetes mellitus (T2DM). Ninety-four elderly patients with T2DM were randomly divided into an RT group (RTG, n = 23), TC group (TCG, n = 24), combination intervention group (CIG, n = 24) and control group (CG, n = 23). All participants were given nutrition and medication. On this basis, RTG, TCG and CIG were administered for 24 weeks (3 times/week, 40 minutes/time). Observation indicators were malondialdehyde (MDA), superoxide dismutase (SOD), 8-hydroxy-2 deoxyguanosine (8-OHdG), fasting plasma glucose (FPG), postprandial plasma glucose (PPG), haemoglobin A1c (HbA1c) and diabetes specific quality of life (DSQL). RT, TC and joint intervention can reduce the oxidative stress damage on elderly patients with T2DM to different degrees, control the levels of blood sugar and blood lipid and improve the quality of life. Compared with single intervention, combination intervention can further reduce the level of oxidative stress but has no additional benefits on blood glucose and lipid control and quality of life.