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Nutritional Support: The Use of Antioxidants in Inflammatory Bowel Disease.

International journal of molecular sciences
January 1, 1970
Sara Jarmakiewicz-Czaja et al. (4 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to explore the potential of essential minerals (selenium, calcium, magnesium, zinc, and iron) in reducing inflammation, enhancing immune function, and modulating gut microbiota in inflammatory bowel disease (IBD).

Results Summary

The study found that these minerals may reduce inflammation, support immune health, and potentially influence intestinal microflora balance, offering promise for IBD treatment. Additionally, calcium showed protective effects against mucosal damage and osteoporosis in IBD patients.

Population

Patients with inflammatory bowel disease (IBD).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (7)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Selenium, calcium, magnesium, zinc, and iron
decrease
inflammation
patients with IBD
-
hold the promise of reducing
#1
Selenium, calcium, magnesium, zinc, and iron
increase
immune function
patients with IBD
-
show the potential to enhance
#2
Selenium, calcium, magnesium, zinc, and iron
increase
balance of intestinal microflora
patients with IBD
-
possibly influence
#3
Selenium, calcium, magnesium, zinc, and iron
decrease
inflammation
patients with IBD
-
could play a crucial role in mitigating
#4
Selenium, calcium, magnesium, zinc, and iron
decrease
complications
patients with IBD
-
could play a crucial role in minimising
#5
Selenium, calcium, magnesium, zinc, and iron
decrease
mucosal damage
patients with IBD
-
protective effect against
#6
calcium
decrease
osteoporosis
patients with IBD
-
protective effect against
#7
Abstract

The problem of treating inflammatory bowel disease continues to be a topic of great interest for researchers. Despite the complexity surrounding their treatment and strategies to prolong periods of remission, there is a promising exploration of various compounds that have potential in combating inflammation and alleviating symptoms. Selenium, calcium, magnesium, zinc, and iron are among these compounds, offering a glimpse of hope in the treatment of IBD. These essential minerals not only hold the promise of reducing inflammation in these diseases, but also show the potential to enhance immune function and possibly influence the balance of intestinal microflora. By potentially modulating the gut microbiota, they may help support overall immune health. Furthermore, these compounds could play a crucial role in mitigating inflammation and minimising complications in patients with IBD. Furthermore, the protective effect of these compounds against mucosal damage in IBD and the protective effect of calcium itself against osteoporosis in this group of patients are notable.

Medical Subject Headings (MeSH)
HumansInflammatory Bowel DiseasesAntioxidantsGastrointestinal MicrobiomeNutritional SupportSeleniumAnimalsMagnesiumZincDietary SupplementsCalcium
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality60/10
Citation Metrics
Total Citations4
Citations/Year4.0
Research Impact Scores
APT Score0.25
Weight Score0.66
Normalized Score0.62
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Nutritional Support: The Use of Antioxidants in Inflammatory... | Panacea Index