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Effects of brief mindfulness training on smoking cue-reactivity in tobacco use disorder: Study protocol for a randomized controlled trial.

PloS one
January 1, 2024
Linlin Cheng et al. (6 authors)
Clinical Trial ProtocolJournal ArticleResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to investigate the impact of brief mindfulness training (BMT) on smoking cue-reactivity and uncover dynamic brain function models in Chinese college students with Tobacco Use Disorder (TUD).

Results Summary

The study is designed as an RCT to assess BMT's effects on smoking craving, EEG indicators, and mindfulness measures, with secondary outcomes including daily smoking behaviors, affect, and impulsivity. Results are pending as the study is ongoing.

Population

Chinese college students with Tobacco Use Disorder (TUD).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Mindfulness interventions focusing on cue-reactivity
decrease
treatment of related dependence
-
-
was effective
#1
Brief mindfulness training (BMT)
neutral
effects
-
-
still need to be examined
#2
BMT intervention
neutral
smoking cue-reactivity
Chinese college students with TUD
-
investigate the impact
#3
brief mindfulness training
neutral
-
experimental group
-
will be administered
#4
Abstract

BACKGROUND: The prevalence of Tobacco Use Disorder (TUD) represents a significant and pressing global public health concern, with far-reaching and deleterious consequences for individuals, communities, and healthcare systems. The craving caused by smoking cue is an important trigger for relapse, fundamentally hindering the cessation of cigarette smoking. Mindfulness interventions focusing on cue-reactivity was effective for the treatment of related dependence. Brief mindfulness training (BMT) meets the short-term needs for intervention but the effects still need to be examined. The objective of the present study is to investigate the impact of BMT intervention on smoking cue-reactivity among Chinese college students with TUD, to uncover the dynamic models of brain function involved in this process. METHOD: A randomized control trial (RCT) based on electroencephalography (EEG) was designed. We aim to recruit 90 participants and randomly assign to the BMT and control group (CON) with 1:1 ratio. A brief mindfulness training will be administered to experimental group. After the intervention, data collection will be conducted in the follow-up stage with 5 timepoints of assessments. EEG data will be recorded during the smoking cue-reactivity task and 'STOP' brief mindfulness task. The primary outcomes include subjective reports of smoking craving, changes in EEG indicators, and mindfulness measures. The secondary outcomes will be daily smoking behaviours, affect and impulsivity, as well as indicators reflecting correlation between mindfulness and smoking cue-reactivity. To evaluate the impact of mindfulness training, a series of linear mixed-effects models will be employed. Specifically, within-group effects will be examined by analysing the longitudinal data. Additionally, the effect size for all statistical measurements will be reported, offering a comprehensive view of the observed effects. DISCUSSION: The current study aims to assess the impact of brief mindfulness-based intervention on smoking cue-reactivity in TUD. It also expected to enhance our understanding of the underlying processes involved in brain function and explore potential EEG biomarkers at multiple time points. TRIAL REGISTRATION: Trial registration number: ChiCTR2300069363, registered on 14 March 2023. Protocol Version 1.0., 10 April 2023.

Medical Subject Headings (MeSH)
AdolescentAdultFemaleHumansMaleYoung AdultCravingCuesElectroencephalographyMindfulnessRandomized Controlled Trials as TopicSmokingSmoking CessationTobacco Use Disorder
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality85/10
Research Impact Scores
APT Score0.05
Weight Score2.53
Normalized Score0.67
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Effects of brief mindfulness training on smoking cue-reactiv... | Panacea Index