Nutrition of aging people with diabetes mellitus: Focus on sarcopenia.
Study Goal
The researchers aimed to evaluate the role of Vitamin D in the combined management of sarcopenia and diabetes, focusing on its potential to improve muscle strength and metabolic health.
Results Summary
The study suggests maintaining adequate levels of Vitamin D as part of nutritional management to promote metabolic health and potentially increase muscle strength, though evidence is insufficient to recommend additional supplementation.
Population
Elderly individuals (aged over 50) with diabetes mellitus and sarcopenia.
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
daily calorie intake that exceeds 30 kcal/kg | increase | muscle synthesis | the elderly | - | ensure | #1 |
protein intake of at least 1-1.2 g/kg/d | increase | muscle synthesis | the elderly | 1-1.2 g/kg/d | is essential | #2 |
branched-amino-acids supplements | increase | protein intake | - | - | can be achieved through | #3 |
restricted protein intake | decrease | diabetic nephropathy | patients with diabetes | - | specific considerations for | #4 |
branched amino acids | increase | insulin resistance | - | - | potential link between | #5 |
prioritizing polyunsaturated fatty acids as a fat source | increase | metabolic health | - | - | promote | #6 |
prioritizing polyunsaturated fatty acids as a fat source | increase | muscle strength | - | - | have demonstrated at least a potential to increase | #7 |
maintaining adequate levels of vitamin D | increase | metabolic health | - | - | promote | #8 |
maintaining adequate levels of vitamin D | increase | muscle strength | - | - | have demonstrated at least a potential to increase | #9 |
additional supplementation | no change | - | - | - | evidence is insufficient to recommend | #10 |
combination of a hypocaloric diet with increased protein intake | neutral | sarcopenic obesity | patients with diabetes and sarcopenia | - | requires | #11 |
As populations age, chronic diseases accumulate, and new health conditions emerge. One noteworthy pair that warrants further evaluation is diabetes mellitus and sarcopenia, given that the latter occurs in 28 % of the population aged over 50 who have diabetes mellitus. The management of both entails nutritional interventions, making the development of unified dietary recommendations an alluring strategy. This review aims to elucidate the current recommendations for the combined management of sarcopenia and diabetes, while featuring elements that require further research. The goal of nutritional management is to improve muscle mass and strength while regulating metabolic risk and glucose levels. To ensure muscle synthesis in the elderly, recommendations align at daily calorie intake that exceeds 30 kcal/kg, with adjustments based on comorbidities. Additionally, a protein intake of at least 1-1.2 g/kg/d is essential, emphasizing both daily and per-meal intake, and can be achieved through diet or branched-amino-acids supplements. Specific considerations for diabetes include restricted protein intake in diabetic nephropathy and exploring the potential link between branched amino acids and insulin resistance. Further recommendations that both promote metabolic health and have demonstrated at least a potential to increase muscle strength include prioritizing polyunsaturated fatty acids as a fat source and maintaining adequate levels of vitamin D. Clinicians should consult their patients on dietary optimization, but evidence is insufficient to recommend additional supplementation. Lastly, an emerging challenge of diabetes and sarcopenia is sarcopenic obesity, which requires the combination of a hypocaloric diet with increased protein intake.