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Nutrition of aging people with diabetes mellitus: Focus on sarcopenia.

Maturitas
July 1, 2024
Almog Shalit et al. (8 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the role of Vitamin D in the combined management of sarcopenia and diabetes, focusing on its potential to improve muscle strength and metabolic health.

Results Summary

The study suggests maintaining adequate levels of Vitamin D as part of nutritional management to promote metabolic health and potentially increase muscle strength, though evidence is insufficient to recommend additional supplementation.

Population

Elderly individuals (aged over 50) with diabetes mellitus and sarcopenia.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (11)
InterventionDirectionEndpointPopulationDosageImpactClaim #
daily calorie intake that exceeds 30 kcal/kg
increase
muscle synthesis
the elderly
-
ensure
#1
protein intake of at least 1-1.2 g/kg/d
increase
muscle synthesis
the elderly
1-1.2 g/kg/d
is essential
#2
branched-amino-acids supplements
increase
protein intake
-
-
can be achieved through
#3
restricted protein intake
decrease
diabetic nephropathy
patients with diabetes
-
specific considerations for
#4
branched amino acids
increase
insulin resistance
-
-
potential link between
#5
prioritizing polyunsaturated fatty acids as a fat source
increase
metabolic health
-
-
promote
#6
prioritizing polyunsaturated fatty acids as a fat source
increase
muscle strength
-
-
have demonstrated at least a potential to increase
#7
maintaining adequate levels of vitamin D
increase
metabolic health
-
-
promote
#8
maintaining adequate levels of vitamin D
increase
muscle strength
-
-
have demonstrated at least a potential to increase
#9
additional supplementation
no change
-
-
-
evidence is insufficient to recommend
#10
combination of a hypocaloric diet with increased protein intake
neutral
sarcopenic obesity
patients with diabetes and sarcopenia
-
requires
#11
Abstract

As populations age, chronic diseases accumulate, and new health conditions emerge. One noteworthy pair that warrants further evaluation is diabetes mellitus and sarcopenia, given that the latter occurs in 28 % of the population aged over 50 who have diabetes mellitus. The management of both entails nutritional interventions, making the development of unified dietary recommendations an alluring strategy. This review aims to elucidate the current recommendations for the combined management of sarcopenia and diabetes, while featuring elements that require further research. The goal of nutritional management is to improve muscle mass and strength while regulating metabolic risk and glucose levels. To ensure muscle synthesis in the elderly, recommendations align at daily calorie intake that exceeds 30 kcal/kg, with adjustments based on comorbidities. Additionally, a protein intake of at least 1-1.2 g/kg/d is essential, emphasizing both daily and per-meal intake, and can be achieved through diet or branched-amino-acids supplements. Specific considerations for diabetes include restricted protein intake in diabetic nephropathy and exploring the potential link between branched amino acids and insulin resistance. Further recommendations that both promote metabolic health and have demonstrated at least a potential to increase muscle strength include prioritizing polyunsaturated fatty acids as a fat source and maintaining adequate levels of vitamin D. Clinicians should consult their patients on dietary optimization, but evidence is insufficient to recommend additional supplementation. Lastly, an emerging challenge of diabetes and sarcopenia is sarcopenic obesity, which requires the combination of a hypocaloric diet with increased protein intake.

Medical Subject Headings (MeSH)
HumansSarcopeniaDietary ProteinsDiabetes MellitusAgingDietary SupplementsAgedVitamin DEnergy IntakeMuscle, SkeletalMuscle StrengthAmino Acids, Branched-ChainDietInsulin Resistance
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality80/10
Citation Metrics
Total Citations3
Citations/Year3.0
Research Impact Scores
APT Score0.25
Weight Score2.77
Normalized Score0.66
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