Panacea Index Logo

Command Palette

Search for a command to run...

The effect of lesser mealworm protein on exercise-induced muscle damage in active older adults: a randomized controlled trial.

The journal of nutrition, health & aging
May 1, 2024
Lotte Koopmans et al. (5 authors)
Journal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to compare the effects of whey protein supplementation versus lesser mealworm-based protein and placebo on exercise-induced muscle damage in older adults after prolonged walking.

Results Summary

The study found no significant differences in muscle damage markers (CK, LDH), handgrip strength, or muscle soreness between whey protein, lesser mealworm protein, and placebo groups after prolonged walking exercise. Whey protein did not attenuate exercise-induced muscle damage compared to the other interventions.

Population

Physically active older adults (>60 years)

Effective Dosage

30 g/day

Duration

12 weeks

Interactions

None mentioned

Extracted Claims (7)
InterventionDirectionEndpointPopulationDosageImpactClaim #
12 weeks lesser mealworm-based (Alphitobius diaperinus) protein supplementation
no change
exercise induced muscle damage
older adults
-
does not attenuate
#1
whey protein supplementation
no change
exercise induced muscle damage
older adults
-
does not attenuate
#2
iso-caloric placebo supplementation
no change
exercise induced muscle damage
older adults
-
does not attenuate
#3
three days of prolonged walking exercise
increase
CK concentrations
older adults
103 [76-161] U/l to 758 [342-1104] U/l
Significant elevations
#4
three days of prolonged walking exercise
increase
LDH concentrations
older adults
202 [175-220] to 283 [252-339] U/l
Significant elevations
#5
three days of prolonged walking exercise
decrease
Hand grip strength
older adults
-
decreased significantly
#6
three days of prolonged walking exercise
increase
muscle soreness
older adults
-
increased
#7
Abstract

OBJECTIVES: We compared the effect of 12 weeks lesser mealworm-based (Alphitobius diaperinus) protein supplementation to whey protein and placebo supplementation on Exercise-Induced Muscle Damage (EIMD) after long-distance walking in older adults. METHODS: in this randomized controlled trial, 70 physically active older adults (>60 years) were randomly allocated to the following groups: I) lesser mealworm protein, II) whey protein or III) iso-caloric placebo. Participants received supplements 11 weeks before and 1 week during a 3-day long-distance walking challenge (30-50 km per day). Blood concentrations of creatinine kinase (CK) and lactate dehydrogenase (LDH), handgrip strength and muscle soreness were measured pre-exercise and directly after each walking bout. RESULTS: Significant elevations of CK concentrations (103 [76-161] U/l to 758 [342-1104] U/l, p < 0.001) and LDH concentrations (202 [175-220] to 283 [252-339] U/l, p < 0.001) were observed following 7h45 min ± 11 min of walking exercise per day, but the magnitude of this effect did not differ among suppletion groups. Hand grip strength decreased significantly (p < 0.001) while muscle soreness increased (p = 0.002) after the first walking day compared to pre-exercise, with no group differences. CONCLUSION: 12-weeks of lesser mealworm-based protein supplementation (30 g/day) does not attenuate exercise induced muscle damage in older adults following three days of prolonged walking exercise in comparison to placebo or whey protein.

Medical Subject Headings (MeSH)
HumansAgedMaleFemaleDietary SupplementsMuscle, SkeletalWhey ProteinsL-Lactate DehydrogenaseMyalgiaHand StrengthWalkingCreatine KinaseMiddle AgedAnimalsExerciseHelminth ProteinsDietary Proteins
Study Links
Quality Scores
SafetyNot Assessed
Efficacy30/10
Quality75/10
Citation Metrics
Total Citations2
Citations/Year2.0
Research Impact Scores
APT Score0.25
Weight Score2.60
Normalized Score0.47
Related Supplements