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Evaluating dietary considerations in hidradenitis suppurativa: a critical examination of existing knowledge.

International journal of dermatology
August 1, 2024
Seçil Vural et al. (6 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to explore the connection between dairy consumption and the progression of hidradenitis suppurativa (HS).

Results Summary

The study suggests that dairy could worsen HS symptoms, potentially through mechanisms linked to inflammation. However, the evidence supporting this connection remains weak, and dietary alterations alone are not considered independent solutions for managing HS.

Population

Patients with hidradenitis suppurativa (HS).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (10)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Mediterranean lifestyle and diet
decrease
HS progression
patients with hidradenitis suppurativa
-
may provide cost-effective and beneficial adjustments
#1
foods with a high glycemic index
increase
HS symptoms
patients with hidradenitis suppurativa
-
could worsen
#2
dairy
increase
HS symptoms
patients with hidradenitis suppurativa
-
could worsen
#3
Zinc
decrease
HS symptoms
patients with hidradenitis suppurativa
-
shows promise as an adjunct therapy
#4
vitamin D deficiency
increase
HS severity
patients with hidradenitis suppurativa
-
suggests a connection
#5
Brewer's yeast-free diet
neutral
HS symptoms
patients with hidradenitis suppurativa
-
merits further investigation
#6
B12 supplementation
neutral
HS symptoms
patients with hidradenitis suppurativa
-
merits further investigation
#7
intermittent fasting
neutral
HS symptoms
patients with hidradenitis suppurativa
-
merits further investigation
#8
reducing the intake of refined sugar
decrease
HS symptoms
patients with hidradenitis suppurativa
-
merits further investigation
#9
reducing the intake of dairy
decrease
HS symptoms
patients with hidradenitis suppurativa
-
merits further investigation
#10
Abstract

Hidradenitis suppurativa (HS) is a chronic condition that can overwhelm patients, and the effectiveness of supplementary dietary treatments remains uncertain. The primary aim of this review is to explore the connection between diet and HS progression. However, it is imperative to note that the evidence supporting a substantial role of the diet in HS remains weak. Dietary alterations alone should not be considered independent solutions for managing HS. Medical therapy continues to be indispensable for adequate treatment. Research indicates that the Mediterranean lifestyle and diet may provide cost-effective and beneficial adjustments when combined with traditional therapies. Conversely, foods with a high glycemic index and dairy could worsen HS symptoms, conceivably through mechanisms linked to insulin resistance and inflammation. Zinc, known for its antioxidant properties, shows promise as an adjunct therapy. Moreover, evidence suggests a connection between vitamin D deficiency and HS severity, although the findings are inconclusive. Brewer's yeast-free diet, B12 supplementation, intermittent fasting, and reducing the intake of refined sugar and dairy merit further investigation. In conclusion, this review highlights the need for additional research because of the lack of standardized reporting of clinical effects in the studies under scrutiny. A deeper exploration of the pathophysiology focusing on dietary modifications and their potential associations with HS severity is essential. Furthermore, it is crucial to recognize that patients' willingness to experiment with new diets makes them vulnerable to fraudulent interventions, highlighting the importance of evidence-based dietary guidance.

Medical Subject Headings (MeSH)
HumansHidradenitis SuppurativaDiet, MediterraneanVitamin D DeficiencySeverity of Illness IndexDairy ProductsDietZincGlycemic IndexDisease ProgressionDietary SupplementsFasting
Study Links
Quality Scores
Safety30
Efficacy20/10
Quality65/10
Citation Metrics
Total Citations4
Citations/Year4.0
Research Impact Scores
APT Score0.50
Weight Score2.50
Normalized Score0.33
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