Effects of self-help mindfulness-based cognitive therapy on mindfulness, symptom change, and suicidal ideation in patients with depression: a randomized controlled study.
Study Goal
The researchers aimed to evaluate the effects of self-help mindfulness-based cognitive therapy (MBCT-SH) on mindfulness, depression symptoms, and suicidal ideation in patients with depression.
Results Summary
MBCT-SH significantly improved mindfulness by week 4 and showed significant reductions in depression symptoms and suicidal ideation by week 8, with sustained effects at 3-month follow-up. It also reduced treatment costs without significantly affecting readmission rates.
Population
Patients with depression (n=97, randomized to MBCT-SH or control).
Effective Dosage
Not specified (eight-week program).
Duration
8 weeks (with follow-ups at 3 and 6 months).
Interactions
None mentioned.
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
self-help mindfulness-based cognitive therapy (MBCT-SH) | increase | mindfulness | patients with depression | - | significantly higher | #1 |
self-help mindfulness-based cognitive therapy (MBCT-SH) | no change | depression symptoms | patients with depression | - | no statistically significant differences | #2 |
self-help mindfulness-based cognitive therapy (MBCT-SH) | no change | suicidal ideation | patients with depression | - | no statistically significant differences | #3 |
self-help mindfulness-based cognitive therapy (MBCT-SH) | increase | mindfulness | patients with depression | - | significant between-group differences | #4 |
self-help mindfulness-based cognitive therapy (MBCT-SH) | decrease | depression symptoms | patients with depression | - | significant between-group differences | #5 |
self-help mindfulness-based cognitive therapy (MBCT-SH) | decrease | suicidal ideation | patients with depression | - | significant between-group differences | #6 |
self-help mindfulness-based cognitive therapy (MBCT-SH) | decrease | per capita treatment costs | patients with depression | 5,298 RMB | lower | #7 |
self-help mindfulness-based cognitive therapy (MBCT-SH) | no change | readmission rates | patients with depression | - | did not differ significantly | #8 |
OBJECTIVE: This study aimed to evaluate the effects of self-help mindfulness-based cognitive therapy (MBCT-SH) on mindfulness, symptom change, and suicidal ideation in patients with depression. METHODS: For this randomized controlled study, 97 patients were randomly assigned to either the MBCT-SH (n = 48) or control (n = 49) group. The Five Facet Mindfulness Questionnaire (FFMQ), Hamilton Depression Rating Scale (HAMD-24), and Suicide Attitude Questionnaire (SAQ) were used to assess mindfulness, depression symptoms, and suicidal ideation, respectively, at baseline (T0), intervention week 4 (T1), intervention week 8 (T2), and 3-month follow-up (T3). The groups were also compared on treatment costs and readmission rates at a 6-month follow-up. RESULTS: In the MBCT-SH group, 46 of 48 participants (96%) completed the eight-week program. At T0, there were no statistically significant between-group differences in demographics, clinical characteristics, FFMQ, HAMD-24, or SAQ. Nor were there statistically significant differences on the HAMD-24 or SAQ between the MBCT-SH and control groups at T1 (p = 0.18 and p = 0.59, respectively), while mindfulness was significantly higher in the MBCT-SH group (t = 2.383, p = 0.019). At T2, there were significant between-group differences on the FFMQ, HAMD-24, and SAQ, all of which remained significant at T3. At the 6-month follow-up, per capita treatment costs were 5,298 RMB lower in the MBCT-SH group compared with the control group, while their readmission rates (6.1% and 4.2%, respectively) did not differ significantly. CONCLUSION: These findings support the feasibility and effectiveness of MBCT-SH among patients with depression. CLINICAL TRIAL REGISTRATION: http://www.chictr.org.cn, ChiCTR2300077850.