Fish Oil Supplementation with Resistance Exercise Training Enhances Physical Function and Cardiometabolic Health in Postmenopausal Women.
Study Goal
The researchers aimed to determine whether fish oil combined with resistance exercise training improves physical function and reduces cardiometabolic risk factors in healthy older women.
Results Summary
Fish oil combined with resistance training significantly improved handgrip strength, reduced blood pressure, triglycerides, inflammatory cytokines (TNF-α and IL-6), and oxidative stress markers (MDA and 8-OHdG), while resistance training alone did not show these effects.
Population
Healthy older women (postmenopausal)
Effective Dosage
Not specified
Duration
8 weeks
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
resistance training with placebo | increase | physical function | healthy older women | - | greatly enhanced | #1 |
resistance training with fish oil | increase | physical function | healthy older women | - | greatly enhanced | #2 |
resistance training with fish oil | increase | handgrip strength | healthy older women | - | substantially increased | #3 |
resistance training with fish oil | decrease | blood pressure | healthy older women | - | significant decreases | #4 |
resistance training with fish oil | decrease | triglyceride | healthy older women | - | significant decreases | #5 |
resistance training with fish oil | decrease | inflammatory cytokines (TNF-α and IL-6) | healthy older women | - | significant decreases | #6 |
resistance training with fish oil | decrease | oxidative stress (MDA and 8-OHdG) levels | healthy older women | - | significant decreases | #7 |
resistance training with placebo | no change | blood pressure, triglyceride, inflammatory cytokines, and oxidative stress levels | healthy older women | - | no detectable changes | #8 |
fish oil administration during 8 wks of resistance exercise training | increase | muscle function | postmenopausal women | - | appears to enhance | #9 |
fish oil administration during 8 wks of resistance exercise training | decrease | risk factors linked to cardiometabolic disorders | postmenopausal women | - | lower | #10 |
Menopause is a condition associated with an increased risk of dysregulation in cardiovascular and metabolic health among older women. While fish oil (FO) has garnered great attention for its health-enhancing properties, its potential for enhancing cardiometabolic health in this demographic remains to be established. The purpose of this study was to determine the clinical efficacy of an 8 wk administration of FO combined with programmed resistance exercise training (RET) on physical function and risk factors associated with cardiometabolic health in healthy older women. Twenty, healthy, older women were randomly assigned to one of the two experimental groups: resistance training with placebo (RET-PL) or RET with fish oil (RET-FO). Physical function, blood pressure (BP), triglyceride (TG), and systemic inflammation and oxidative stress biomarkers were assessed before and after the intervention. Statistical significance was set at p ≤ 0.05. Physical function was greatly enhanced in both RET and RET-FO. Handgrip strength substantially increased only in RET-FO. RET-FO exhibited significant decreases in BP, TG, inflammatory cytokines (TNF-α and IL-6), and oxidative stress (MDA and 8-OHdG) levels, while no detectable changes were found in RET-PL. Our findings indicate that FO administration during 8 wks of RET appears to enhance muscle function and lower risk factors linked to cardiometabolic disorders in postmenopausal women.