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Beta-hydroxy-β-methyl butyrate-supplemented diet for broiler chickens is more conducive to dietary protein reduction than a leucine-supplemented diet until 21 days old.

Journal of the science of food and agriculture
February 1, 2024
Canan Kop Bozbay et al. (3 authors)
Journal ArticleAnimal Study
Study Details

Study Goal

The researchers aimed to evaluate the effects of l-leucine (LLPD) or HMB (HLPD) supplementation in a low-protein diet on performance, carcass weight, muscle yield, meat quality, and intestinal morphometry in broiler chickens.

Results Summary

The low-protein diet (LPD) decreased body weight gain and feed intake while increasing feed conversion ratio compared to a standard protein diet (SPD). HMB supplementation (HLPD) improved dressing percentage and intestinal morphometry but did not affect meat quality.

Population

Broiler chickens (until 21 days old).

Effective Dosage

Not specified.

Duration

42 days (intervention until 21 days old, with follow-up until 42 days).

Interactions

None mentioned.

Extracted Claims (18)
InterventionDirectionEndpointPopulationDosageImpactClaim #
low-protein diet (20%, LPD)
decrease
body weight gain
broiler chickens
-
decreased
#1
low-protein diet (20%, LPD)
decrease
feed intake (FI)
broiler chickens
-
decreased
#2
low-protein diet (20%, LPD)
increase
feed conversion ratio
broiler chickens
-
increased
#3
l-leucine supplementation in a low-protein diet (LLPD)
no change
FI
broiler chickens
-
did not affect
#4
l-leucine supplementation in a low-protein diet (LLPD)
decrease
body weight gain
broiler chickens
-
decreased
#5
l-leucine supplementation in a low-protein diet (LLPD)
increase
feed conversion ratio
broiler chickens
-
increased
#6
low-protein diet (20%, LPD)
decrease
body and muscle weights
broiler chickens
-
had lower
#7
HMB supplementation in a low-protein diet (HLPD)
increase
dressing percentage
broiler chickens
-
increased
#8
low-protein diet (20%, LPD)
decrease
serum insulin-like growth factor-1 content
broiler chickens
-
decreased
#9
low-protein diet (20%, LPD)
decrease
duodenal villus height
broiler chickens
-
was smaller
#10
l-leucine supplementation in a low-protein diet (LLPD)
decrease
duodenal villus height
broiler chickens
-
was smaller
#11
HMB supplementation in a low-protein diet (HLPD)
decrease
duodenal villus width
broiler chickens
-
had lower
#12
HMB supplementation in a low-protein diet (HLPD)
increase
duodenal crypt depth
broiler chickens
-
were higher
#13
HMB supplementation in a low-protein diet (HLPD)
increase
ileal mucosal thickness
broiler chickens
-
were higher
#14
HMB supplementation in a low-protein diet (HLPD)
increase
ileal villus height
broiler chickens
-
enhanced
#15
l-leucine supplementation in a low-protein diet (LLPD)
increase
ileal villus height
broiler chickens
-
enhanced
#16
l-leucine supplementation in a low-protein diet (LLPD)
no change
meat quality traits
broiler chickens
-
did not affect
#17
HMB supplementation in a low-protein diet (HLPD)
no change
meat quality traits
broiler chickens
-
did not affect
#18
Abstract

BACKGROUND: Dietary l-leucine or its metabolite 𝛽-hydroxy-𝛽-methylbutyrate (HMB) has a crucial role in the muscle protein metabolism of broilers during the first few-week growing period. The present study aimed to evaluate the effects of l-leucine (LLPD) or HMB (HLPD) supplementation in a low-protein diet (20%, LPD) until 21 days old on performance, carcass weight, muscle yield and meat quality, as well as intestinal morphometry, in broiler chickens. RESULTS: From days 1-42, LPD decreased body weight gain and feed intake (FI) and increased feed conversion ratio compared to a standard protein diet (22%, SPD). The LLPD and HLPD did not affect FI, but the LLPD decreased the body weight gain and increased the feed conversion ratio compared to the SPD. The LPD group had lower body and muscle weights than other groups. Compared to LPD, HLPD increased dressing percentage. The LPD decreased the serum insulin-like growth factor-1 content compared to the SPD and LLPD. The duodenal villus height of the LPD and LLPD broilers was smaller than those of the SPD and HLPD birds. The HLPD broilers had lower duodenal villus width than the SPD birds. The duodenal crypt depth and ileal mucosal thickness were higher in the HLPD group than in other groups. The HLPD and LLPD enhanced the ileal villus height compared to the SPD. The LLPD and HLPD treatments did not affect meat quality traits compared to the SPD treatment. CONCLUSION: Dietary HMB could be a conducive approach to reducing dietary protein for broilers until 21 days old. © 2023 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Medical Subject Headings (MeSH)
AnimalsChickensLeucineDietary SupplementsDietDietary ProteinsBody WeightAnimal FeedAnimal Nutritional Physiological Phenomena
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality80/10
Citation Metrics
Total Citations1
Citations/Year1.0
Research Impact Scores
APT Score0.05
Weight Score1.95
Normalized Score0.66
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