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Advances in the beneficial effects of nutrition on stroke-related Sarcopenia: A narrative review.

Medicine
January 1, 1970
Zhiqiang Gao et al. (2 authors)
ReviewJournal ArticleHuman Study
Study Details

Study Goal

The researchers aimed to review the role of nutrition, including Vitamin D, in improving malnutrition and muscle mass in stroke-related sarcopenia.

Results Summary

The study suggests that supplementation with whey protein combined with Vitamin D may improve malnutrition status, increase muscle mass, and delay or prevent stroke-related sarcopenia. However, no specific efficacy data on Vitamin D alone were provided.

Population

Patients with stroke-related sarcopenia.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (24)
InterventionDirectionEndpointPopulationDosageImpactClaim #
supplementation with essential amino acids
increase
malnutrition status
stroke patients
-
may improve
#1
whey protein combined with vitamin D
increase
malnutrition status
stroke patients
-
may improve
#2
high energy diet
increase
malnutrition status
stroke patients
-
may improve
#3
avoiding Polypharmacy
increase
malnutrition status
stroke patients
-
may improve
#4
increasing physical activity level
increase
malnutrition status
stroke patients
-
may improve
#5
reducing sedentary lifestyle
increase
malnutrition status
stroke patients
-
may improve
#6
supplementation with essential amino acids
increase
muscle mass
stroke patients
-
may increase
#7
whey protein combined with vitamin D
increase
muscle mass
stroke patients
-
may increase
#8
high energy diet
increase
muscle mass
stroke patients
-
may increase
#9
avoiding Polypharmacy
increase
muscle mass
stroke patients
-
may increase
#10
increasing physical activity level
increase
muscle mass
stroke patients
-
may increase
#11
reducing sedentary lifestyle
increase
muscle mass
stroke patients
-
may increase
#12
supplementation with essential amino acids
increase
skeletal muscle index
stroke patients
-
may increase
#13
whey protein combined with vitamin D
increase
skeletal muscle index
stroke patients
-
may increase
#14
high energy diet
increase
skeletal muscle index
stroke patients
-
may increase
#15
avoiding Polypharmacy
increase
skeletal muscle index
stroke patients
-
may increase
#16
increasing physical activity level
increase
skeletal muscle index
stroke patients
-
may increase
#17
reducing sedentary lifestyle
increase
skeletal muscle index
stroke patients
-
may increase
#18
supplementation with essential amino acids
decrease
development of stroke-related sarcopenia
stroke patients
-
may delay or even prevent
#19
whey protein combined with vitamin D
decrease
development of stroke-related sarcopenia
stroke patients
-
may delay or even prevent
#20
high energy diet
decrease
development of stroke-related sarcopenia
stroke patients
-
may delay or even prevent
#21
avoiding Polypharmacy
decrease
development of stroke-related sarcopenia
stroke patients
-
may delay or even prevent
#22
increasing physical activity level
decrease
development of stroke-related sarcopenia
stroke patients
-
may delay or even prevent
#23
reducing sedentary lifestyle
decrease
development of stroke-related sarcopenia
stroke patients
-
may delay or even prevent
#24
Abstract

Stroke is one of the most common causes of disability in adults. Sarcopenia is a syndrome characterized by progressive systemic muscle loss and functional decline. The decrease in skeletal muscle mass and muscle function throughout the body after stroke cannot be explained by neurological motor disorders due to brain injury alone, it is considered to be a secondary sarcopenia known as stroke-related sarcopenia. Mounting evidences showed that stroke-related sarcopenia might promote the occurrence and development of sarcopenia through various pathogenesis such as muscle atrophy, dysphagia, inflammation, and malnutrition, etc. At present, the main indicators used to assess malnutrition in patients with stroke-related sarcopenia include temporalis muscle thickness, calf circumference, phase angle, geriatric nutritional risk index and mini-nutritional assessment short-form, etc. Currently, there is no particularly effective method to curb its progression, but supplementation with essential amino acids, whey protein combined with vitamin D, high energy diet, avoiding Polypharmacy, as well as increasing physical activity level and reducing sedentary lifestyle may improve the malnutrition status of stroke patients, and increase the muscle mass and skeletal muscle index, further delay or even prevent the development of stroke-related sarcopenia. This article reviews the latest research progress on the characteristics, epidemiology, pathogenesis and the role of nutrition in stroke-related sarcopenia, so as to provide reference for the clinical treatment and rehabilitation of stroke-related sarcopenia.

Medical Subject Headings (MeSH)
HumansAgedSarcopeniaNutritional StatusMuscle, SkeletalMalnutritionStroke
Study Links
Quality Scores
SafetyNot Assessed
Efficacy70/10
Quality65/10
Citation Metrics
Total Citations8
Citations/Year4.0
Relative Citation Ratio3.05
NIH Percentile85.3%
Research Impact Scores
APT Score0.75
Weight Score1.44
Normalized Score0.61
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