Advances in the beneficial effects of nutrition on stroke-related Sarcopenia: A narrative review.
Study Goal
The researchers aimed to review the role of nutrition, including Vitamin D, in improving malnutrition and muscle mass in stroke-related sarcopenia.
Results Summary
The study suggests that supplementation with whey protein combined with Vitamin D may improve malnutrition status, increase muscle mass, and delay or prevent stroke-related sarcopenia. However, no specific efficacy data on Vitamin D alone were provided.
Population
Patients with stroke-related sarcopenia.
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
supplementation with essential amino acids | increase | malnutrition status | stroke patients | - | may improve | #1 |
whey protein combined with vitamin D | increase | malnutrition status | stroke patients | - | may improve | #2 |
high energy diet | increase | malnutrition status | stroke patients | - | may improve | #3 |
avoiding Polypharmacy | increase | malnutrition status | stroke patients | - | may improve | #4 |
increasing physical activity level | increase | malnutrition status | stroke patients | - | may improve | #5 |
reducing sedentary lifestyle | increase | malnutrition status | stroke patients | - | may improve | #6 |
supplementation with essential amino acids | increase | muscle mass | stroke patients | - | may increase | #7 |
whey protein combined with vitamin D | increase | muscle mass | stroke patients | - | may increase | #8 |
high energy diet | increase | muscle mass | stroke patients | - | may increase | #9 |
avoiding Polypharmacy | increase | muscle mass | stroke patients | - | may increase | #10 |
increasing physical activity level | increase | muscle mass | stroke patients | - | may increase | #11 |
reducing sedentary lifestyle | increase | muscle mass | stroke patients | - | may increase | #12 |
supplementation with essential amino acids | increase | skeletal muscle index | stroke patients | - | may increase | #13 |
whey protein combined with vitamin D | increase | skeletal muscle index | stroke patients | - | may increase | #14 |
high energy diet | increase | skeletal muscle index | stroke patients | - | may increase | #15 |
avoiding Polypharmacy | increase | skeletal muscle index | stroke patients | - | may increase | #16 |
increasing physical activity level | increase | skeletal muscle index | stroke patients | - | may increase | #17 |
reducing sedentary lifestyle | increase | skeletal muscle index | stroke patients | - | may increase | #18 |
supplementation with essential amino acids | decrease | development of stroke-related sarcopenia | stroke patients | - | may delay or even prevent | #19 |
whey protein combined with vitamin D | decrease | development of stroke-related sarcopenia | stroke patients | - | may delay or even prevent | #20 |
high energy diet | decrease | development of stroke-related sarcopenia | stroke patients | - | may delay or even prevent | #21 |
avoiding Polypharmacy | decrease | development of stroke-related sarcopenia | stroke patients | - | may delay or even prevent | #22 |
increasing physical activity level | decrease | development of stroke-related sarcopenia | stroke patients | - | may delay or even prevent | #23 |
reducing sedentary lifestyle | decrease | development of stroke-related sarcopenia | stroke patients | - | may delay or even prevent | #24 |
Stroke is one of the most common causes of disability in adults. Sarcopenia is a syndrome characterized by progressive systemic muscle loss and functional decline. The decrease in skeletal muscle mass and muscle function throughout the body after stroke cannot be explained by neurological motor disorders due to brain injury alone, it is considered to be a secondary sarcopenia known as stroke-related sarcopenia. Mounting evidences showed that stroke-related sarcopenia might promote the occurrence and development of sarcopenia through various pathogenesis such as muscle atrophy, dysphagia, inflammation, and malnutrition, etc. At present, the main indicators used to assess malnutrition in patients with stroke-related sarcopenia include temporalis muscle thickness, calf circumference, phase angle, geriatric nutritional risk index and mini-nutritional assessment short-form, etc. Currently, there is no particularly effective method to curb its progression, but supplementation with essential amino acids, whey protein combined with vitamin D, high energy diet, avoiding Polypharmacy, as well as increasing physical activity level and reducing sedentary lifestyle may improve the malnutrition status of stroke patients, and increase the muscle mass and skeletal muscle index, further delay or even prevent the development of stroke-related sarcopenia. This article reviews the latest research progress on the characteristics, epidemiology, pathogenesis and the role of nutrition in stroke-related sarcopenia, so as to provide reference for the clinical treatment and rehabilitation of stroke-related sarcopenia.