Nutritional considerations for a new era: A CF foundation position paper.
Study Goal
The researchers aimed to summarize current understanding of salt homeostasis in the context of cystic fibrosis nutrition, particularly in the era of highly effective modulator therapy (HEMT).
Results Summary
The abstract does not provide specific findings on salt's effects, only that salt homeostasis was one of the four workgroup topics reviewed.
Population
Individuals with cystic fibrosis (pwCF).
Effective Dosage
Not available
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
cystic fibrosis transmembrane regulator highly effective modulator therapy (HEMT) | increase | life expectancy | People with CF (pwCF) | - | People with CF are living longer | #1 |
traditional high fat, high calorie CF diet | decrease | nutritional and cardiovascular health | People with CF (pwCF) | - | may have negative nutritional and cardiovascular consequences | #2 |
- | decrease | diet quality | Individuals with CF | - | may have poor diet quality | #3 |
- | decrease | food security | Individuals with CF | - | may have food insecurity | #4 |
- | decrease | body image | Individuals with CF | - | may have distorted body image | #5 |
- | increase | incidence of eating disorders | Individuals with CF | - | may have a higher incidence of eating disorders | #6 |
- | increase | overweight and obesity | Individuals with CF | - | An increase in overweight and obesity may lead to new considerations for nutritional management | #7 |
overweight and obesity | decrease | pulmonary and cardiometabolic parameters | Individuals with CF | - | may lead to potential effects on pulmonary and cardiometabolic parameters | #8 |
OBJECTIVE: To provide interim advice and considerations to the CF Community around CF nutrition in the current era. METHODS: The Cystic Fibrosis (CF) Foundation organized a multidisciplinary committee to develop a Nutrition Position Paper based on the rapidly changing nutrition landscape in CF, due in part to widespread use of cystic fibrosis transmembrane regulator highly effective modulator therapy (HEMT). Four workgroups were formed: Weight Management, Eating Behavior/Food Insecurity, Salt Homeostasis and Pancreatic Enzyme use. Each workgroup conducted their own focused review of the literature. RESULTS: The committee summarized current understanding of issues pertaining to the four workgroup topics and provided 6 key take-aways around CF Nutrition in the new era. CONCLUSION: People with CF (pwCF) are living longer, particularly with the advent of HEMT. The traditional high fat, high calorie CF diet may have negative nutritional and cardiovascular consequences as pwCF age. Individuals with CF may have poor diet quality, food insecurity, distorted body image, and an higher incidence of eating disorders. An increase in overweight and obesity may lead to new considerations for nutritional management, given potential effects of overnutrition on pulmonary and cardiometabolic parameters.