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The Role of Diet in Children with Psoriasis: Emerging Evidence and Current Issues.

Nutrients
January 1, 1970
Edoardo De Simoni et al. (6 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the potential benefits of a gluten-free diet, among other dietary regimens, in managing psoriasis and its associated comorbidities in pediatric and adult patients.

Results Summary

The study suggests that a gluten-free diet, along with Mediterranean and low-calorie diets, may positively influence disease control in psoriasis patients, particularly in reducing associated conditions like celiac disease and obesity. However, the abstract does not provide specific data on the magnitude of these effects.

Population

Pediatric and adult patients with psoriasis, particularly those with associated conditions like celiac disease and obesity.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (11)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Mediterranean diet
increase
disease control
adult patients with psoriasis and adequate pharmacological therapy
-
may positively affect
#1
gluten-free diet
increase
disease control
adult patients with psoriasis and adequate pharmacological therapy
-
may positively affect
#2
low-calorie diet
increase
disease control
adult patients with psoriasis and adequate pharmacological therapy
-
may positively affect
#3
Mediterranean, gluten-free, or low-calorie diet
neutral
-
children with psoriasis
-
may play a role
#4
Mediterranean, gluten-free, or low-calorie diet
decrease
psychological stress
pediatric psoriasis
-
may be positively influenced
#5
Mediterranean, gluten-free, or low-calorie diet
decrease
celiac disease
pediatric psoriasis
-
may be positively influenced
#6
Mediterranean, gluten-free, or low-calorie diet
decrease
obesity
pediatric psoriasis
-
may be positively influenced
#7
tailor-made dietary strategy
increase
good growth
-
-
ensuring
#8
tailor-made dietary strategy
increase
adequate intake of essential micro- and macronutrients
-
-
ensuring
#9
tailor-made dietary strategy
decrease
pro-inflammatory biochemical profile
psoriasis disease
-
impacting
#10
tailor-made dietary strategy
decrease
associated cardiovascular risk
psoriasis disease
-
impacting
#11
Abstract

Psoriasis is an immune-mediated inflammatory systemic disease with skin tropism and chronic relapsing course; it is associated with an increased cardiovascular risk and with many metabolic comorbidities, emerging during childhood in 22-33% of cases. Diet influences the presentation and the clinical course of inflammatory diseases, including psoriasis; in particular, it was shown that a Mediterranean, gluten-free, or low-calorie diet may positively affect disease control in adult patients with psoriasis and adequate pharmacological therapy. These three dietary regimens may play a role also in children with psoriasis. It has been demonstrated that pediatric psoriasis is associated with psychological stress, celiac disease, and obesity, which may be positively influenced by these dietary regimens, respectively. Therefore, the expertise of multiple health figures (gastroenterologists, nutritionists, pediatricians, dermatologists) is required to plan a tailor-made dietary strategy, ensuring good growth, through an adequate intake of essential micro- and macronutrients and, at the same time, impacting the pro-inflammatory biochemical profile and on the associated cardiovascular risk of psoriasis disease.

Medical Subject Headings (MeSH)
AdultHumansChildPsoriasisObesityComorbidityDiet, Gluten-FreeCaloric Restriction
Study Links
Quality Scores
SafetyNot Assessed
Efficacy70/10
Quality65/10
Citation Metrics
Total Citations3
Citations/Year1.5
Relative Citation Ratio0.95
NIH Percentile48.3%
Research Impact Scores
APT Score0.50
Weight Score1.34
Normalized Score0.61
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