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Interaction between β-glucans and gut microbiota: a comprehensive review.

Critical reviews in food science and nutrition
January 1, 2024
Reza Karimi et al. (5 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to review the effects of Beta-glucans on gut microbiota, including their metabolism, impact on microbial populations, gut infections, prebiotic effects, and fermentation properties.

Results Summary

The study found that Beta-glucans modulate gut microbiota, enhance intestinal fermentation, produce beneficial metabolites, and exhibit prebiotic effects, suggesting therapeutic potential for gut health.

Population

Not specified (general human gut microbiota)

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Diet
neutral
composition and function of GMB
humans
-
can regulate
#1
Dietary fibers
increase
different health benefits
-
-
can induce
#2
Dietary fibers
increase
beneficial GMB
-
-
stimulation of
#3
β-glucans (BGs)
increase
therapeutic roles on gut health
-
-
can have
#4
β-glucans (BGs)
neutral
GMB
-
-
modulation of
#5
β-glucans (BGs)
increase
different metabolites
-
-
production of
#6
Abstract

Gut microbiota (GMB) in humans plays a crucial role in health and diseases. Diet can regulate the composition and function of GMB which are associated with different human diseases. Dietary fibers can induce different health benefits through stimulation of beneficial GMB. β-glucans (BGs) as dietary fibers have gained much interest due to their various functional properties. They can have therapeutic roles on gut health based on modulation of GMB, intestinal fermentation, production of different metabolites, and so on. There is an increasing interest in food industries in commercial application of BG as a bioactive substance into food formulations. The aim of this review is considering the metabolizing of BGs by GMB, effects of BGs on the variation of GMB population, influence of BGs on the gut infections, prebiotic effects of BGs in the gut, in vivo and in vitro fermentation of BGs and effects of processing on BG fermentability.

Medical Subject Headings (MeSH)
Gastrointestinal MicrobiomeHumansbeta-GlucansFermentationPrebioticsDietary FiberAnimalsDiet
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality75/10
Citation Metrics
Total Citations2
Citations/Year2.0
Research Impact Scores
APT Score0.05
Weight Score1.30
Normalized Score0.69
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