Post Hoc Analysis of a Randomized Controlled Trial on Fasting and Plant-Based Diet in Rheumatoid Arthritis (NutriFast): Nutritional Supply and Impact on Dietary Behavior.
Study Goal
The study aimed to compare nutrient supply and dietary behaviors during a plant-based diet combined with time-restricted eating versus standard dietary recommendations in rheumatoid arthritis patients, but did not specifically focus on Vitamin A.
Results Summary
The abstract does not mention any findings related to Vitamin A.
Population
Rheumatoid arthritis patients
Effective Dosage
Not available
Duration
12 weeks
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
7-day fast followed by an 11-week plant-based diet (PBD) including time-restricted eating (TRE) | decrease | total saturated fat intake | rheumatoid arthritis patients | 15.9 ± 7.7 vs. 23.2 ± 10.3 g/day | consumed significantly less | #1 |
7-day fast followed by an 11-week plant-based diet (PBD) including time-restricted eating (TRE) | no change | energy intake | rheumatoid arthritis patients | - | had similar | #2 |
7-day fast followed by an 11-week plant-based diet (PBD) including time-restricted eating (TRE) | no change | carbohydrate intake | rheumatoid arthritis patients | - | had similar | #3 |
7-day fast followed by an 11-week plant-based diet (PBD) including time-restricted eating (TRE) | no change | sugar intake | rheumatoid arthritis patients | - | had similar | #4 |
7-day fast followed by an 11-week plant-based diet (PBD) including time-restricted eating (TRE) | no change | fiber intake | rheumatoid arthritis patients | - | had similar | #5 |
7-day fast followed by an 11-week plant-based diet (PBD) including time-restricted eating (TRE) | no change | protein intake | rheumatoid arthritis patients | - | had similar | #6 |
12-week anti-inflammatory diet following official German guidelines (German Nutrition Society, DGE) | no change | energy intake | rheumatoid arthritis patients | - | had similar | #7 |
12-week anti-inflammatory diet following official German guidelines (German Nutrition Society, DGE) | no change | carbohydrate intake | rheumatoid arthritis patients | - | had similar | #8 |
12-week anti-inflammatory diet following official German guidelines (German Nutrition Society, DGE) | no change | sugar intake | rheumatoid arthritis patients | - | had similar | #9 |
12-week anti-inflammatory diet following official German guidelines (German Nutrition Society, DGE) | no change | fiber intake | rheumatoid arthritis patients | - | had similar | #10 |
12-week anti-inflammatory diet following official German guidelines (German Nutrition Society, DGE) | no change | protein intake | rheumatoid arthritis patients | - | had similar | #11 |
This study aimed at comparing the nutrient supply and dietary behaviors during a plant-based diet (PBD) combined with time-restricted eating (TRE) to standard dietary recommendations in rheumatoid arthritis patients. In this open-label, randomized, controlled clinical trial, patients were assigned to either a 7-day fast followed by an 11-week PBD including TRE (A) or a 12-week anti-inflammatory diet following official German guidelines (German Nutrition Society, DGE) (B). Dietary habits were assessed by 3-day food records at weeks -1, 4 and 9 and food frequency questionnaires. 41 out of 53 participants were included in a post-hoc per protocol analysis. Both groups had similar energy, carbohydrate, sugar, fiber and protein intake at week 4. Group A consumed significantly less total saturated fat than group B (15.9 ± 7.7 vs. 23.2 ± 10.3 g/day;