The Effects of a New Integrated and Multidisciplinary Cognitive Rehabilitation Program Based on Mindfulness and Reminiscence Therapy in Patients with Parkinson's Disease and Mild Cognitive Impairment: A Pilot Study.
Study Goal
The researchers aimed to determine whether a mindfulness-based rehabilitation program, including reminiscence activities, could improve cognitive and behavioral outcomes in patients with Parkinson's disease (PD) and mild cognitive impairment (MCI).
Results Summary
The study found significant improvements in MoCA global scores, memory sub-scale scores, and BDI-II cognitive and affective factors in the experimental group (MILC-tr) compared to the usual structured program. The results suggest mindfulness-based rehabilitation, including reminiscence therapy, may be effective for PD and MCI patients.
Population
Patients with Parkinson's disease (PD) and mild cognitive impairment (MCI).
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
mindfulness-based rehabilitation program | increase | MoCA global score | patients affected by PD and MCI in MILC-tr group | x2 = 4.000, p = 0.046 | significant improvement | #1 |
mindfulness-based rehabilitation program | increase | MoCA memory sub-scale score | patients affected by PD and MCI in MILC-tr group | x2 = 4.571, p = 0.033 | significant improvement | #2 |
mindfulness-based rehabilitation program | decrease | BDI-II cognitive and affective factors | patients affected by PD and MCI in MILC-tr group | x2 = 4.000, p = 0.046 | significant improvement | #3 |
mindfulness-based rehabilitation program | increase | MoCA memory sub-scale score | patients affected by PD and MCI | U = 190.50, p = 0.035 | significant difference | #4 |
Background: Mindfulness trainings have shown promising results as treatment for behavioural symptoms in several pathologies. In addition, mindfulness protocols induced an improvement in memory and attention. Therefore, mindfulness could be an effective intervention for patients affected by Parkinson's disease (PD) and mild cognitive impairment (MCI), who are characterized by both behavioural and cognitive dysfunctions. Methods: We assessed differences in Montreal Cognitive Assessment (MoCA) scores and in Beck Depression Inventory II (BDI-II) scores in patients affected by PD and MCI enrolled in two different rehabilitation programs (an experimental vs. an usual structured program for cognitive rehabilitation). Participants in the experimental group (MILC-tr) underwent innovative rehabilitation program involving mindfulness and reminiscence activities. Assessments were performed before (T0) and at the end of the rehabilitation program (T1). Results: Friedman test showed a significant improvement between timepoints in MoCA global score (x2 = 4.000, p = 0.046), MoCA memory sub-scale score (x2 = 4.571, p = 0.033), and BDI-II cognitive and affective factors (x2 = 4.000, p = 0.046) only for patients in MILC-tr group. Mann-Whitney test showed a significant difference between group comparing differences in Δ scores between T0 and T1 in the MoCA memory sub-scale score (U = 190.50, p = 0.035). Conclusions: Mindfulness-based rehabilitation programs could be effective in patients affected by PD and MCI.