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Creatine supplementation combined with blood flow restriction training enhances muscle thickness and performance: a randomized, placebo-controlled, and double-blind study.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
January 1, 1970
Rayssa Sousa-Silva et al. (7 authors)
Randomized Controlled TrialJournal ArticleHuman StudyClinical
Study Details

Study Goal

The researchers aimed to compare the effects of creatine versus placebo supplementation on muscle strength, thickness, endurance, and body composition using blood flow restriction versus traditional resistance training.

Results Summary

The abstract does not provide specific results, but the study compared creatine and placebo effects across different training paradigms.

Population

Seventeen healthy males.

Effective Dosage

Not specified in the abstract.

Duration

8 weeks.

Interactions

None mentioned.

Extracted Claims (8)
InterventionDirectionEndpointPopulationDosageImpactClaim #
creatine (CR) supplementation
neutral
muscle strength
Seventeen healthy males
-
effects
#1
creatine (CR) supplementation
neutral
muscle thickness
Seventeen healthy males
-
effects
#2
creatine (CR) supplementation
neutral
muscle endurance
Seventeen healthy males
-
effects
#3
creatine (CR) supplementation
neutral
body composition
Seventeen healthy males
-
effects
#4
placebo (PL) supplementation
neutral
muscle strength
Seventeen healthy males
-
effects
#5
placebo (PL) supplementation
neutral
muscle thickness
Seventeen healthy males
-
effects
#6
placebo (PL) supplementation
neutral
muscle endurance
Seventeen healthy males
-
effects
#7
placebo (PL) supplementation
neutral
body composition
Seventeen healthy males
-
effects
#8
Abstract

This study aimed to compare the effects of an 8-week creatine (CR) or placebo (PL) supplementation on muscle strength, thickness, endurance, and body composition employing different training paradigms with blood flow restriction (BFR) vs. traditional resistance training (TRAD). Seventeen healthy males were randomized between the PL (

Medical Subject Headings (MeSH)
MaleHumansCreatineDouble-Blind MethodBlood Flow Restriction TherapyMuscle, SkeletalMuscle StrengthResistance TrainingDietary SupplementsRegional Blood Flow
Study Links
Quality Scores
SafetyNot Assessed
Efficacy65/10
Quality75/10
Citation Metrics
Total Citations3
Citations/Year1.5
Relative Citation Ratio1.52
NIH Percentile65.6%
Research Impact Scores
APT Score0.25
Weight Score1.46
Normalized Score0.61
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Creatine supplementation combined with blood flow restrictio... | Panacea Index