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Eat for better cognition in older adults at risk for Alzheimer's disease.

Nutrition (Burbank, Los Angeles County, Calif.)
May 1, 2023
Yuye Wang et al. (3 authors)
Journal ArticleReviewResearch Support, Non-U.S. Gov'tHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the role of diet, including a modified Mediterranean-ketogenic diet, in protecting cognition during the preclinical stages of Alzheimer's disease.

Results Summary

The study found that interventions like the modified Mediterranean-ketogenic diet, nuts, vitamin B, and Bifidobacterium breve A1 were beneficial for cognitive protection, suggesting dietary approaches as effective treatments for older adults at risk for Alzheimer's disease.

Population

Older adults at risk for Alzheimer's disease.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (5)
InterventionDirectionEndpointPopulationDosageImpactClaim #
modified Mediterranean-ketogenic diet
increase
cognition protection
-
-
beneficial to
#1
nuts
increase
cognition protection
-
-
beneficial to
#2
vitamin B
increase
cognition protection
-
-
beneficial to
#3
Bifidobacterium breve A1
increase
cognition protection
-
-
beneficial to
#4
Eating, rather than just taking medicine
neutral
-
older adults at risk for Alzheimer's disease
-
suggested to be an effective treatment method
#5
Abstract

Alzheimer's disease is a worldwide public health problem. However, the treatment method and treatment effects are limited. The stages of preclinical Alzheimer's disease are thought to be a better intervention period. Thus, in this review, food is given focus and the intervention stage put forward. We summarized the role of diet, nutrient supplementation, and microbioecologics in cognitive decline and found that interventions such as modified Mediterranean-ketogenic diet, nuts, vitamin B, and Bifidobacterium breve A1 are beneficial to cognition protection. Eating, rather than just taking medicine, is suggested to be an effective treatment method for older adults at risk for Alzheimer's disease.

Medical Subject Headings (MeSH)
HumansAgedAlzheimer DiseaseCognitionCognitive DysfunctionVitamin B ComplexDiet, Mediterranean
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality65/10
Citation Metrics
Total Citations2
Citations/Year1.0
Relative Citation Ratio0.63
NIH Percentile33.7%
Research Impact Scores
APT Score0.25
Weight Score2.23
Normalized Score0.63
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