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Low-Grade Inflammation and Role of Anti-Inflammatory Diet in Childhood Obesity.

International journal of environmental research and public health
January 17, 2023
Ewelina Polak-Szczybyło
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to review the impact of low-grade inflammation (LGI) on health and explore the potential role of anti-inflammatory nutrition in preventing and treating obesity-related disorders in children.

Results Summary

The abstract suggests that an anti-inflammatory diet may help mitigate low-grade inflammation linked to pediatric obesity and related conditions, but notes a limited number of studies specifically assessing this in childhood obesity. The findings are theoretical and lack specific clinical data.

Population

Children with obesity and related disorders (e.g., insulin resistance, type 2 diabetes, NAFLD).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
excess body weight
increase
low-grade inflammation
-
-
are related to
#1
low-grade inflammation
increase
diseases
-
-
linking
#2
diet rich in anti-inflammatory nutrients
increase
maintaining health
-
-
may be the key to
#3
diet rich in anti-inflammatory nutrients
increase
recovery
-
-
may be the key to
#4
Abstract

At present, pediatric obesity is a significant public health concern. We have seen a surge of disorders that are obesity-related, e.g., insulin resistance (IR), type 2 diabetes mellitus (T2DM), high blood pressure, heart disease, stroke, cancer, non-alcoholic fatty liver disease (NAFLD), autoimmune disorders and many more. The mechanisms linking these diseases to excess body weight are related to low-grade inflammation (LGI). Although there is a limited number of studies assessing this immune process in childhood obesity, they indicate its significant importance for the health of future generations. There is a need for more research into the prevention and treatment of low-grade inflammation in childhood. The aim of this review is to present and discuss the process of "cold" inflammation, and its impact on health and anti-inflammation nutrition. A diet rich in anti-inflammatory nutrients may be the key to maintaining health, as well as recovery.

Medical Subject Headings (MeSH)
HumansChildPediatric ObesityDiabetes Mellitus, Type 2InflammationDietNon-alcoholic Fatty Liver DiseaseInsulin ResistanceAnti-Inflammatory Agents
Study Links
Quality Scores
SafetyNot Assessed
Efficacy60/10
Quality50/10
Citation Metrics
Total Citations9
Citations/Year4.5
Relative Citation Ratio2.48
NIH Percentile80.6%
Research Impact Scores
APT Score0.50
Weight Score2.15
Normalized Score0.54
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