Mindful yoga intervention as add-on to treatment as usual for young women with major depressive disorder: Results from a randomized controlled trial.
Study Goal
The researchers aimed to determine whether adding a 9-week mindful yoga intervention (MYI) to treatment as usual (TAU) would reduce depression symptoms in young women with major depressive disorder (MDD).
Results Summary
Adding MYI to TAU did not significantly reduce depression symptoms, lower MDD diagnosis rates, or improve quality of life compared to TAU-only. No indirect effects were observed through potential mediators except for a slight improvement in self-compassion.
Population
Young women aged 18-34 with major depressive disorder (MDD).
Effective Dosage
Not specified
Duration
9 weeks
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
mindful yoga intervention (MYI) as add-on to treatment as usual (TAU) | no change | depression symptoms | young women (18-34 years) with major depressive disorder (MDD) | - | did not lead to greater reduction | #1 |
mindful yoga intervention (MYI) as add-on to treatment as usual (TAU) | no change | MDD diagnosis | young women (18-34 years) with major depressive disorder (MDD) | - | did not lead to lower rate | #2 |
mindful yoga intervention (MYI) as add-on to treatment as usual (TAU) | no change | quality of life in various domains of functioning | young women (18-34 years) with major depressive disorder (MDD) | - | did not lead to increase | #3 |
mindful yoga intervention (MYI) as add-on to treatment as usual (TAU) | no change | rumination | young women (18-34 years) with major depressive disorder (MDD) | - | no indirect effects through | #4 |
mindful yoga intervention (MYI) as add-on to treatment as usual (TAU) | no change | self-criticism | young women (18-34 years) with major depressive disorder (MDD) | - | no indirect effects through | #5 |
mindful yoga intervention (MYI) as add-on to treatment as usual (TAU) | no change | intolerance of uncertainty | young women (18-34 years) with major depressive disorder (MDD) | - | no indirect effects through | #6 |
mindful yoga intervention (MYI) as add-on to treatment as usual (TAU) | no change | perceived body awareness | young women (18-34 years) with major depressive disorder (MDD) | - | no indirect effects through | #7 |
mindful yoga intervention (MYI) as add-on to treatment as usual (TAU) | no change | dispositional mindfulness | young women (18-34 years) with major depressive disorder (MDD) | - | no indirect effects through | #8 |
mindful yoga intervention (MYI) as add-on to treatment as usual (TAU) | no change | attentional bias (AB) | young women (18-34 years) with major depressive disorder (MDD) | - | no indirect effects through | #9 |
mindful yoga intervention (MYI) as add-on to treatment as usual (TAU) | no change | depression-related self-associations | young women (18-34 years) with major depressive disorder (MDD) | - | no indirect effects through | #10 |
mindful yoga intervention (MYI) as add-on to treatment as usual (TAU) | no change | depression symptoms | young women | - | appeared not more efficacious than TAU-only in reducing | #11 |
OBJECTIVE: To examine the added value of a 9-week mindful yoga intervention (MYI) as add-on to treatment as usual (TAU) in reducing depression for young women (18-34 years) with major depressive disorder (MDD). METHOD: Randomized controlled trial (RCT; n = 171) comparing TAU + MYI with TAU-only. Assessments were at baseline, postintervention, and at 6- and 12-month follow-up. Primary outcome measures were clinician-rated and self-reported symptoms of depression, together with a diagnostic interview to establish MDD diagnosis that was restricted to the baseline and 12-month follow-up assessments. Quality of life in various domains was assessed as secondary outcome measure. As potential mediators for treatment efficacy, we included self-report measures of rumination, self-criticism, self-compassion, intolerance of uncertainty, perceived body awareness and dispositional mindfulness, together with behavioral measures of attentional bias (AB) and depression-related self-associations. RESULTS: Adding MYI to TAU did not lead to greater reduction of depression symptoms, lower rate of MDD diagnosis or increase in quality of life in various domains of functioning at post and follow-up assessments. There were no indirect effects through any of the potential mediators, with the exception of self-compassion. CONCLUSION: Adding MYI to TAU appeared not more efficacious than TAU-only in reducing depression symptoms in young women. (PsycInfo Database Record (c) 2023 APA, all rights reserved).