Cognitive impairment, anxiety and depression: a map of Cochrane evidence relevant to rehabilitation for people with post COVID-19 condition.
Study Goal
The researchers aimed to evaluate the effectiveness of manual acupressure massage as a rehabilitation intervention for anxiety and depression in various health conditions, potentially relevant for post COVID-19 condition (PCC).
Results Summary
Manual acupressure massage was found to be effective for anxiety and depression in specific diseases, with evidence ranging from very low to moderate quality. The study grouped it among other interventions like exercise, yoga, and acupuncture, which showed varying degrees of efficacy.
Population
Participants with various health conditions, including cancer, stroke, and chronic obstructive pulmonary disease, among others.
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
exercises | increase | cognitive impairment | participants with stroke, cancer, Parkinson's disease, and other health conditions | - | improved | #1 |
cognitive and attention-specific training | increase | cognitive impairment | participants with stroke, cancer, Parkinson's disease, and other health conditions | - | improved | #2 |
computerized cognition-based training | increase | cognitive impairment | participants with stroke, cancer, Parkinson's disease, and other health conditions | - | improved | #3 |
exercise training | decrease | anxiety and depression | participants with cancer, stroke, chronic obstructive pulmonary disease, and other health conditions | - | resulted effective | #4 |
physical activity | decrease | anxiety and depression | participants with cancer, stroke, chronic obstructive pulmonary disease, and other health conditions | - | resulted effective | #5 |
yoga | decrease | anxiety and depression | participants with cancer, stroke, chronic obstructive pulmonary disease, and other health conditions | - | resulted effective | #6 |
acupuncture | decrease | anxiety and depression | specific diseases | - | found effective | #7 |
animal-assisted therapy | decrease | anxiety and depression | specific diseases | - | found effective | #8 |
aromatherapy | decrease | anxiety and depression | specific diseases | - | found effective | #9 |
educational programs | decrease | anxiety and depression | specific diseases | - | found effective | #10 |
home-based multidimensional survivorship programs | decrease | anxiety and depression | specific diseases | - | found effective | #11 |
manual acupressure massage | decrease | anxiety and depression | specific diseases | - | found effective | #12 |
memory rehabilitation | decrease | anxiety and depression | specific diseases | - | found effective | #13 |
non-invasive brain stimulation | decrease | anxiety and depression | specific diseases | - | found effective | #14 |
pulmonary rehabilitation | decrease | anxiety and depression | specific diseases | - | found effective | #15 |
telerehabilitation | decrease | anxiety and depression | specific diseases | - | found effective | #16 |
INTRODUCTION: Currently, no evidence exists on specific treatments for post COVID-19 condition (PCC). However, rehabilitation interventions that are effective for similar symptoms in other health conditions could be applied to people with PCC. With this overview of systematic reviews with mapping, we aimed to describe the Cochrane evidence on rehabilitation interventions proposed for cognitive impairment, anxiety and depression in different health conditions that can be relevant for PCC. EVIDENCE ACQUISITION: We searched the last five years' Cochrane Systematic Review (CSRs) using the terms "cognitive impairment," "depressive disorder," "anxiety disorder," their synonyms and variants, and "rehabilitation" in the Cochrane Library. We extracted and summarized the available evidence using a map. We grouped the included CSRs for health conditions and interventions, indicating the effect and the quality of evidence. EVIDENCE SYNTHESIS: We found 3596 CSRs published between 2016 and 2021, and we included 17 on cognitive impairment and 37 on anxiety and depression. For cognitive impairment, we found 7 CSRs on participants with stroke, 3 with cancer, 2 with Parkinson's disease, and one each for five other health conditions. Each intervention improved a different domain, and included exercises, cognitive and attention-specific training, and computerized cognition-based training (from very low to high-quality evidence). For anxiety and depression, we found 10 CSRs including participants with cancer, 8 with stroke, 3 with chronic obstructive pulmonary disease, and 2 or 1 each in 11 other health conditions. Exercise training, physical activity and yoga resulted effective in several pathologies (very low- to moderate-quality evidence). In specific diseases, we found effective acupuncture, animal-assisted therapy, aromatherapy, educational programs, home-based multidimensional survivorship programs, manual acupressure massage, memory rehabilitation, non-invasive brain stimulation, pulmonary rehabilitation, and telerehabilitation (very low- to moderate-quality evidence). CONCLUSIONS: These results are the first step of indirect evidence able to generate helpful hypotheses for clinical practice and future research. They served as the basis for the three recommendations on treatments for these PCC symptoms published in the current WHO Guidelines for clinical practice.