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Patient Blood Management programs for post-partum hemorrhage.

Best practice & research. Clinical anaesthesiology
December 1, 2022
Carlos Delgado et al. (2 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the role of iron supplementation in optimizing hemoglobin concentration before delivery and treating postpartum anemia after severe PPH.

Results Summary

Iron supplementation was found effective in optimizing hemoglobin levels pre-delivery and treating postpartum anemia. Techniques like acute normovolemic hemodilution and intraoperative cell salvage were also noted as safe and effective in reducing blood transfusion needs.

Population

Pregnant women, particularly those at risk for or experiencing postpartum hemorrhage.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (5)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Iron supplementation
increase
hemoglobin concentration
patients before delivery
-
should be used to optimize
#1
Iron supplementation
decrease
anemia
patients in the postpartum period after severe PPH
-
can also be used to treat
#2
acute normovolemic hemodilution
decrease
allogeneic blood transfusion
patients during or after surgical procedures
-
can be effective techniques to reduce
#3
intraoperative cell salvage
decrease
allogeneic blood transfusion
patients during or after surgical procedures
-
can be effective techniques to reduce
#4
these strategies
no change
-
the pregnant population
-
appear to be safe when used
#5
Abstract

Patient blood management (PBM) strategies aim to maintain hemoglobin concentration, optimize hemostasis, and minimize blood loss to improve patient outcomes. Because postpartum hemorrhage (PPH) is a leading cause of maternal mortality and blood product utilization, PBM principles can be applied in its therapeutic approach. First, pre-operative identification of risk factors for PPH and identification of peri-delivery anemia should be conducted. Iron supplementation should be used to optimize hemoglobin concentration before delivery; it can also be used to treat anemia in the postpartum period after severe PPH. Both acute normovolemic hemodilution and intraoperative cell salvage can be effective techniques to reduce allogeneic blood transfusion during or after surgical procedures. Furthermore, these strategies appear to be safe when used in the pregnant population.

Medical Subject Headings (MeSH)
PregnancyFemaleHumansPostpartum HemorrhageBlood TransfusionAnemiaHemoglobinsPostpartum PeriodBlood Loss, Surgical
Study Links
Quality Scores
Safety85
Efficacy80/10
Quality75/10
Citation Metrics
Total Citations3
Citations/Year1.0
Relative Citation Ratio0.56
NIH Percentile30.3%
Research Impact Scores
APT Score0.25
Weight Score2.33
Normalized Score0.81
Related Supplements
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