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Update on treatments for anxiety-related disorders.

Current opinion in psychiatry
January 1, 1970
Hyun Jeong Lee et al. (2 authors)
ReviewJournal ArticleHuman Study
Study Details

Study Goal

The researchers aimed to compare the efficacy of mindfulness-based interventions with other psychological therapies, particularly cognitive behavioral therapy (CBT), for treating anxiety-related disorders.

Results Summary

The study found that mindfulness-based interventions were among the psychological therapies tried for anxiety disorders, but most therapies, including mindfulness, were comparable to CBT without proving superior.

Population

Individuals with anxiety-related disorders (specific disorders not detailed).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (14)
InterventionDirectionEndpointPopulationDosageImpactClaim #
agomelatine
decrease
generalized anxiety disorder (GAD)
-
-
has demonstrated efficacy
#1
ketamine, psilocybin and cannabidiol
decrease
anxiety disorders
-
-
are in the process of gathering evidence in support of the treatment
#2
various psychological treatments for anxiety disorders (mindfulness-based intervention, acceptance and commitment therapy, psychodynamic therapy, emotion-focused therapy and dialectical behavioural therapy)
no change
-
-
-
have not proven superior
#3
cognitive behavioural therapy (CBT)
no change
-
-
-
most therapies have not proven superior to
#4
Repetitive transcranial magnetic stimulation (rTMS)
decrease
generalized anxiety disorder (GAD)
-
-
was effective
#5
transcranial direct current stimulation (tDCS)
decrease
social anxiety disorder (SAD) and GAD
-
-
was effective
#6
transcranial direct current stimulation (tDCS)
increase
exposure therapy for specific fears
-
-
augmented
#7
Internet and mobile-based interventions
no change
-
-
-
have comparable efficacy
#8
face-to-face therapy
no change
-
-
-
Internet and mobile-based interventions have comparable efficacy to
#9
other psychological therapies for anxiety disorders
no change
-
-
-
were comparable to but not superior
#10
cognitive behavioural therapy (CBT)
no change
-
-
-
most therapies were comparable to but not superior to
#11
rTMS and tDCS
decrease
GAD
-
-
show early promise
#12
Most internet or mobile app based psychological therapies
no change
-
-
-
can be considered as alternatives
#13
in-person face-to-face therapy
no change
-
-
-
some can be considered as alternatives to
#14
Abstract

PURPOSE OF REVIEW: This review examines recent evidence that informs the treatment of anxiety-related disorders. RECENT FINDINGS: In addition to selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), and benzodiazepines, agomelatine has demonstrated efficacy in treating generalized anxiety disorder (GAD). Other novel products, such as ketamine, psilocybin and cannabidiol, are in the process of gathering evidence in support of the treatment of anxiety disorders. In psychological therapy, various psychological treatments for anxiety disorders, such as mindfulness-based intervention, acceptance and commitment therapy, psychodynamic therapy, emotion-focused therapy and dialectical behavioural therapy, have been tried. Still, most therapies have not proven superior to cognitive behavioural therapy (CBT). In very preliminary findings: Repetitive transcranial magnetic stimulation (rTMS) was effective in GAD; transcranial direct current stimulation (tDCS) was effective for social anxiety disorder (SAD) and GAD and augmented exposure therapy for specific fears. Internet and mobile-based interventions have comparable efficacy to face-to-face therapy. SUMMARY: Pharmacotherapy of anxiety disorders is expanding to novel products. Despite trying other psychological therapies for anxiety disorders, most therapies were comparable to but not superior to CBT. rTMS and tDCS were also used and show early promise for GAD, but further studies are needed. Most internet or mobile app based psychological therapies were based on CBT, and some can be considered as alternatives to in-person face-to-face therapy.

Medical Subject Headings (MeSH)
HumansAcceptance and Commitment TherapyTranscranial Direct Current StimulationAnxiety DisordersSelective Serotonin Reuptake InhibitorsAnxiety
Study Links
Quality Scores
SafetyNot Assessed
Efficacy70/10
Quality80/10
Citation Metrics
Total Citations15
Citations/Year7.5
Relative Citation Ratio4.51
NIH Percentile91.8%
Research Impact Scores
APT Score0.75
Weight Score1.70
Normalized Score0.64
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