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Eccentric resistance training with neurological conditions: A meta analysis.

Gait & posture
February 1, 2023
Whitley J Stone et al. (5 authors)
Meta-AnalysisJournal ArticleReviewHuman Study
Study Details

Study Goal

The researchers sought to compare the efficacy of eccentric resistance training (ERT) against conventional therapeutic modalities or weightlifting on walking speed, Timed Up and Go (TUG), and maximum voluntary isometric contraction (MVIC) in individuals with neurological conditions.

Results Summary

The study found no significant difference between ERT and traditional therapies or weightlifting on measured outcomes (TUG, MVIC, walking speed), suggesting ERT is as effective as traditional methods for improving movement in clinical populations. ERT may be preferable due to lower metabolic demand and greater work volume capacity.

Population

Individuals with neurological conditions (n = 297 across 13 studies).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (3)
InterventionDirectionEndpointPopulationDosageImpactClaim #
eccentric resistance training (ERT)
no change
performance (TUG, MVIC, walking speed)
individuals with neurological conditions
SMD: 0.136; 95 % CI: -0.0002, 0.050
revealed a small, albeit non-significant effect on performance
#1
eccentric resistance training (ERT)
no change
measured outcomes
clinical populations
-
appears to be no difference
#2
eccentric resistance training (ERT)
no change
movement
clinical populations
-
is as effective as
#3
Abstract

BACKGROUND: People with neurological conditions are exposed to muscle wasting resulting in reduced strength and endurance. Both deficiencies negatively impact gait and balance, each of which can be benefited by strengthening exercises. Unfortunately, people with neurological conditions often do not have the ability to perform traditional weight training as their endurance and strength fail to meet the minimum threshold for improvement. An alternative to traditional, full range of motion lifting is eccentric resistance training (ERT). RESEARCH QUESTION: The current systematic review and meta-analysis sought to evaluate the efficacy of ERT against conventional therapeutic modalities or weightlifting on walking speed, Timed Up and Go (TUG), and maximum voluntary isometric contraction (MVIC) in individuals with neurological conditions. METHODS: Web of Science, PubMed, and Academic Search Complete were searched until September 1, 2020, followed by a manual search on December 3, 2021. Publications were included if they were peer reviewed, available in English, consisted of a pre-specified neurological disorder, involved human subjects, had an eccentric and "traditional" therapy; and reported at least one of the outcome measures at both pre- and post-intervention. RESULTS: Thirteen studies of human subjects (n = 297) and 47 standardized mean differences (SMD) were included in the multilevel model analysis. The analysis revealed a small, albeit non-significant effect on performance (TUG, MVIC, walking speed) when comparing traditional therapies and ERT (SMD: 0.136; 96; 95 % CI: -0.0002, 0.050). SIGNIFICANCE: There appears to be no difference between ERT and traditional therapy or weightlifting on measured outcomes. In this way, ERT is as effective as traditional therapeutics and full range of motion weightlifting to improve movement in clinical populations. Practitioners working with populations with neurological conditions may consider supplementing or replacing traditional strengthening activities with ERT as clients can complete greater volumes of work with lower metabolic demand.

Medical Subject Headings (MeSH)
HumansResistance TrainingExercise TherapyExerciseGaitWalking Speed
Study Links
Quality Scores
SafetyNot Assessed
Efficacy65/10
Quality75/10
0
Research Impact Scores
APT Score0.05
Weight Score2.19
Normalized Score0.61
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