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The effectiveness of mindfulness-based interventions for ruminative thinking: A systematic review and meta-analysis of randomized controlled trials.

Journal of affective disorders
January 1, 1970
Lingyun Mao et al. (5 authors)
Meta-AnalysisSystematic ReviewJournal ArticleReviewResearch Support, Non-U.S. Gov'tHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the effectiveness of mindfulness-based interventions for reducing ruminative thinking and enhancing mindfulness levels, comparing them to cognitive behavioral therapy (CBT).

Results Summary

Mindfulness-based interventions significantly reduced ruminative thinking and enhanced mindfulness levels, though they were not significantly more effective than CBT. Subgroups with higher proportions of females showed more significant improvements in ruminative thinking.

Population

4,229 patients across 61 studies, including individuals with depression, students, cancer patients, healthy adults, and clinical patients.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (13)
InterventionDirectionEndpointPopulationDosageImpactClaim #
mindfulness-based interventions
decrease
ruminative thinking
patients
SMD = -0.534, 95 % CI = [-0.675, -0.394]
revealed a significant intervention effect
#1
mindfulness-based interventions
no change
-
-
SMD = 0.009, 95%CI = [-0.239, 0.258]
no significant difference
#2
mindfulness-based interventions
increase
level of mindfulness
-
SMD = 0.495, 95 % CI = [0.343, 0.647]
significantly enhanced
#3
mindfulness-based interventions
no change
level of mindfulness
-
SMD = 0.158, 95%CI = [-0.087, 0.403]
not significant
#4
mindfulness-based interventions
decrease
ruminative thinking
subgroups with >65 % of females
SMD = -0.534, 95%CI = [-0.681, -0.386]
showed significant improvement
#5
mindfulness-based interventions
decrease
ruminative thinking
subgroups with 80 % of females
SMD = -0.462, 95%CI = [-0.590, -0.334]
showed significant improvement
#6
mindfulness-based interventions
neutral
-
depression
-
significant intervention effects
#7
mindfulness-based interventions
neutral
-
students
-
significant intervention effects
#8
mindfulness-based interventions
neutral
-
cancer
-
significant intervention effects
#9
mindfulness-based interventions
neutral
-
healthy adults
-
significant intervention effects
#10
mindfulness-based interventions
neutral
-
clinical patients
-
significant intervention effects
#11
mindfulness-based interventions
neutral
-
various participant ages
-
significant intervention effects
#12
mindfulness-based interventions
neutral
-
various intervention periods
-
significant intervention effects
#13
Abstract

OBJECTIVE: To systematically evaluate the effectiveness of mindfulness-based interventions for ruminative thinking. METHODS: Cochrane Library, Web of Science, Embase, EBSCO, PubMed and Science Direct databases were searched to include randomized controlled trials of mindfulness-based interventions for rumination that met the criteria. The Rumination scale was used as the primary outcome indicator, and the secondary outcome indicator included the Mindfulness scale. An evaluation of bias risk was conducted to identify possible sources of bias based on methodological and clinical factors. Stata 16.0 software was used to perform meta-analysis, subgroup analysis, sensitivity analysis, meta-regression analysis and publication bias detection of the extracted data. RESULTS: A total of 61 studies with 4229 patients were included. Meta-analysis results revealed a significant intervention effect on ruminative thinking (SMD = -0.534, 95 % CI = [-0.675, -0.394], z = -7.449, P < 0.001). However, there was no significant difference between mindfulness-based interventions and CBT (SMD = 0.009, 95%CI = [-0.239, 0.258], z = 0.073, P = 0.941). Meta-analysis showed that mindfulness-based interventions significantly enhanced the level of mindfulness (SMD = 0.495, 95 % CI = [0.343, 0.647], z = 6.388, P < 0.001), while it was not significant compared to CBT (SMD = 0.158, 95%CI = [-0.087, 0.403], z = 1.266, P = 0.205). The two subgroups with >65 % (SMD = -0.534, 95%CI = [-0.681, -0.386], z = -7.081, P < 0.001) and 80 % (SMD = -0.462, 95%CI = [-0.590, -0.334], z = -7.071, P < 0.001) of females showed significant improvement in ruminative thinking. There were significant intervention effects for depression, students, cancer, healthy adults, and clinical patients. Significant intervention effects were demonstrated for various participant ages and intervention periods. CONCLUSION: This study confirmed the feasibility of mindfulness-based interventions in improving ruminative thinking and enhancing the level of mindfulness. However, the effectiveness of mindfulness-based interventions was not significant compared to CBT. The two subgroups with a higher proportion of females showed a more significant improvement in ruminative thinking, whereas there were no significant differences in participant characteristics, age, and the duration of intervention.

Medical Subject Headings (MeSH)
HumansAdultFemaleMindfulnessAnxietyRandomized Controlled Trials as TopicStudentsNeoplasms
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality90/10
Citation Metrics
Total Citations19
Citations/Year9.5
Relative Citation Ratio6.91
NIH Percentile95.9%
Research Impact Scores
APT Score0.75
Weight Score1.87
Normalized Score0.72
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