A Health Care Professional Delivered Low Carbohydrate Diet Program Reduces Body Weight, Haemoglobin A1c, Diabetes Medication Use and Cardiovascular Risk Markers-A Single-Arm Intervention Analysis.
Study Goal
The researchers aimed to evaluate the effectiveness of a healthcare professional-delivered low-carbohydrate diet program (Diversa Health Program) in improving obesity and type-2 diabetes management among adults in Australia.
Results Summary
The study found significant reductions in body weight (average 6 kg) and HbA1c levels (from 6.0% to 5.6%), with the greatest improvements observed in individuals with higher baseline obesity or HbA1c. Medication use for diabetes also decreased among participants.
Population
511 adults (average age 57.1 ± 13.7 years) in Australia with obesity or type-2 diabetes.
Effective Dosage
Not specified
Duration
Average participation duration was 218 ± 207 days.
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
health care professional delivered low-carbohydrate diet program (Diversa Health Program) | decrease | body weight | 511 adults (Age:57.1 ± 13.7 [SD] yrs) who participated between January 2017−August 2021 for ≥30 days | from 92.3 ± 23.0 to 86.3 ± 21.1 kg | reduced | #1 |
health care professional delivered low-carbohydrate diet program (Diversa Health Program) | decrease | HbA1c | 511 adults (Age:57.1 ± 13.7 [SD] yrs) who participated between January 2017−August 2021 for ≥30 days | from 6.0 ± 1.2 to 5.6 ± 0.7% | reduced | #2 |
health care professional delivered low-carbohydrate diet program (Diversa Health Program) | decrease | body weight | members with a classification of normal weight (n = 67) | 0.9 ± 2.8 kg (1.3%) | weight loss | #3 |
health care professional delivered low-carbohydrate diet program (Diversa Health Program) | decrease | body weight | members with a classification of overweight (n = 122) | 4.5 ± 4.3 kg (5.7%) | weight loss | #4 |
health care professional delivered low-carbohydrate diet program (Diversa Health Program) | decrease | body weight | members with a classification of obese (n = 307) | 7.9 ± 7.2 kg (7.5%) | weight loss | #5 |
health care professional delivered low-carbohydrate diet program (Diversa Health Program) | decrease | HbA1c | members with a commencing HbA1c of <5.7% (n = 110) | -0.1 ± 0.2% | reduced | #6 |
health care professional delivered low-carbohydrate diet program (Diversa Health Program) | decrease | HbA1c | members with a commencing HbA1c of 5.7−6.4% (n = 55) | -0.3 ± 0.3% | reduced | #7 |
health care professional delivered low-carbohydrate diet program (Diversa Health Program) | decrease | HbA1c | members with a commencing HbA1c of ≥6.5% (n = 48) | -1.4 ± 1.3% | reduced | #8 |
health care professional delivered low-carbohydrate diet program (Diversa Health Program) | decrease | HbA1c | members with a commencing HbA1c ≥6.5% | 90% | experienced a HbA1c reduction | #9 |
health care professional delivered low-carbohydrate diet program (Diversa Health Program) | decrease | HbA1c | members with a commencing HbA1c ≥6.5% | 54% | achieved a final HbA1c < 6.5% | #10 |
health care professional delivered low-carbohydrate diet program (Diversa Health Program) | decrease | diabetes medications prescribed | members with inclusion of metformin | from 124 medications prescribed to 63 members to 82 medications prescribed to 51 members | reduced | #11 |
health care professional delivered low-carbohydrate diet program (Diversa Health Program) | decrease | diabetes medications prescribed | members with exclusion of metformin | from 82 medications prescribed to 42 members to 35 medications prescribed to 26 members | reduced | #12 |
health care professional delivered low-carbohydrate diet program (Diversa Health Program) | decrease | weight loss and glycaemic control | individuals with worse baseline parameters | greatest improvements and clinical relevance | can facilitate weight loss and improve glycaemic control | #13 |
This study examined the effectiveness of a health care professional delivered low-carbohydrate diet program (Diversa Health Program) aiming to improve obesity/type-2-diabetes management for people living in Australia. 511 adults (Age:57.1 ± 13.7 [SD] yrs) who participated between January 2017−August 2021 for ≥30 days with pre-post data collected for ≥1 key outcome variable (body weight and HbA1c) were included in the analysis. Average participation duration was 218 ± 207 days with 5.4 ± 3.9 reported consultation visits. Body weight reduced from 92.3 ± 23.0 to 86.3 ± 21.1 kg (n = 506, p < 0.001). Weight loss was 0.9 ± 2.8 kg (1.3%), 4.5 ± 4.3 kg (5.7%) and 7.9 ± 7.2 kg (7.5%), respectively, for those with a classification of normal weight (n = 67), overweight (n = 122) and obese (n = 307) at commencement. HbA1c reduced from 6.0 ± 1.2 to 5.6 ± 0.7% (n = 212, p < 0.001). For members with a commencing HbA1c of <5.7% (n = 110), 5.7−6.4% (n = 55), and ≥6.5% (n = 48), HbA1c reduced −0.1 ± 0.2%, −0.3 ± 0.3%, and −1.4 ± 1.3%, respectively. For members with a commencing HbA1c ≥6.5%, 90% experienced a HbA1c reduction and 54% achieved a final HbA1c < 6.5%. With inclusion and exclusion of metformin, respectively, 124 and 82 diabetes medications were prescribed to 63 and 42 members that reduced to 82 and 35 medications prescribed to 51 and 26 members at final visit. A health care professional delivered low-carbohydrate diet program can facilitate weight loss and improve glycaemic control with greatest improvements and clinical relevance in individuals with worse baseline parameters.