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DASH diet vs. DASH diet plus physical activity in older patients with type 2 diabetes and high blood pressure: A randomized clinical trial.

Nutrition and health
June 1, 2024
Vanessa L P de Oliveira et al. (8 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to evaluate the effects of the DASH diet, with and without physical activity guidance, on blood pressure, glycemic control, lipid profile, weight, and body composition in older patients with type 2 diabetes mellitus (T2DM) and hypertension.

Results Summary

Both groups (DASH diet alone and DASH diet with physical activity) showed significant reductions in weight, BMI, and waking diastolic blood pressure, but no differences were found between the groups in changes to weight, BMI, body composition, glycemic control, lipid profile, or insulin sensitivity. The DASHPED group increased physical activity by 1721 steps/day, but this did not lead to additional benefits over diet alone.

Population

Patients aged 60 years or older with T2DM and uncontrolled hypertension.

Effective Dosage

Not specified

Duration

16 weeks

Interactions

None mentioned

Extracted Claims (16)
InterventionDirectionEndpointPopulationDosageImpactClaim #
DASH diet with physical activity guidance (DASHPED)
increase
physical activity
older patients with type 2 diabetes mellitus (T2DM) and hypertension
1721 steps/day
had an mean increase
#1
DASH diet (DASH)
decrease
weight
older patients with type 2 diabetes mellitus (T2DM) and hypertension
-
significantly reduced
#2
DASH diet (DASH)
decrease
BMI
older patients with type 2 diabetes mellitus (T2DM) and hypertension
-
significantly reduced
#3
DASH diet (DASH)
decrease
waking diastolic pressures on ambulatory blood pressure monitoring
older patients with type 2 diabetes mellitus (T2DM) and hypertension
-
significantly reduced
#4
DASH diet with physical activity guidance (DASHPED)
decrease
weight
older patients with type 2 diabetes mellitus (T2DM) and hypertension
-
significantly reduced
#5
DASH diet with physical activity guidance (DASHPED)
decrease
BMI
older patients with type 2 diabetes mellitus (T2DM) and hypertension
-
significantly reduced
#6
DASH diet with physical activity guidance (DASHPED)
decrease
waking diastolic pressures on ambulatory blood pressure monitoring
older patients with type 2 diabetes mellitus (T2DM) and hypertension
-
significantly reduced
#7
DASH diet with physical activity guidance (DASHPED)
decrease
sleeping diastolic pressure
older patients with type 2 diabetes mellitus (T2DM) and hypertension
-
trend of reduced
#8
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED)
no change
weight
older patients with type 2 diabetes mellitus (T2DM) and hypertension
-
did not differ
#9
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED)
no change
BMI
older patients with type 2 diabetes mellitus (T2DM) and hypertension
-
did not differ
#10
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED)
no change
muscle mass
older patients with type 2 diabetes mellitus (T2DM) and hypertension
-
did not differ
#11
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED)
no change
body fat
older patients with type 2 diabetes mellitus (T2DM) and hypertension
-
did not differ
#12
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED)
no change
waist-hip ratio
older patients with type 2 diabetes mellitus (T2DM) and hypertension
-
did not differ
#13
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED)
no change
glycemic control
older patients with type 2 diabetes mellitus (T2DM) and hypertension
-
did not differ
#14
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED)
no change
lipid profile
older patients with type 2 diabetes mellitus (T2DM) and hypertension
-
did not differ
#15
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED)
no change
insulin sensitivity
older patients with type 2 diabetes mellitus (T2DM) and hypertension
-
did not differ
#16
Abstract

BACKGROUND AND AIMS: To evaluate the effect of lifestyle modification by adopting a DASH diet, with and without physical activity guidance, on blood pressure, glycemic control, lipid profile, weight, and body composition in older patients with type 2 diabetes mellitus (T2DM) and hypertension. METHODS AND RESULTS: For this randomized clinical trial, we recruited patients aged 60 years or older with T2DM and uncontrolled hypertension. One group (DASH) received only DASH dietary guidance, while the other group (DASHPED) received dietary guidance and encouragement to walk with a pedometer. Outcomes of interest were (1) blood pressure, (2) physical activity, (3) weight, body mass index (BMI), and body composition, and (4) biochemical variables. Measurements were taken at baseline and 16 weeks after the intervention. We included 35 patients in the analysis. At the end of the study, the DASHPED group had an mean increase in physical activity of 1721 steps/day. Both groups displayed significantly reduced weight, BMI, and waking diastolic pressures on ambulatory blood pressure monitoring after the intervention. A trend of reduced sleeping diastolic pressure was found in the DASHPED group. Changes in weight, BMI, muscle mass, body fat, waist-hip ratio, glycemic control, lipid profile, and insulin sensitivity did not differ between the groups. CONCLUSION: There was no difference in outcomes between the group that only dieted and the group that also performed increased physical activity, despite a significant increase in exercise. This reinforces the importance of dietary changes in immediate blood pressure control.

Medical Subject Headings (MeSH)
HumansDiabetes Mellitus, Type 2MaleFemaleAgedExerciseHypertensionMiddle AgedBlood PressureBody Mass IndexDietary Approaches To Stop HypertensionBody CompositionBlood GlucoseLipidsBody Weight
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality70/10
Citation Metrics
Total Citations2
Citations/Year2.0
Research Impact Scores
APT Score0.75
Weight Score2.49
Normalized Score0.64