DASH diet vs. DASH diet plus physical activity in older patients with type 2 diabetes and high blood pressure: A randomized clinical trial.
Study Goal
The researchers aimed to evaluate the effects of the DASH diet, with and without physical activity guidance, on blood pressure, glycemic control, lipid profile, weight, and body composition in older patients with type 2 diabetes mellitus (T2DM) and hypertension.
Results Summary
Both groups (DASH diet alone and DASH diet with physical activity) showed significant reductions in weight, BMI, and waking diastolic blood pressure, but no differences were found between the groups in changes to weight, BMI, body composition, glycemic control, lipid profile, or insulin sensitivity. The DASHPED group increased physical activity by 1721 steps/day, but this did not lead to additional benefits over diet alone.
Population
Patients aged 60 years or older with T2DM and uncontrolled hypertension.
Effective Dosage
Not specified
Duration
16 weeks
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
DASH diet with physical activity guidance (DASHPED) | increase | physical activity | older patients with type 2 diabetes mellitus (T2DM) and hypertension | 1721 steps/day | had an mean increase | #1 |
DASH diet (DASH) | decrease | weight | older patients with type 2 diabetes mellitus (T2DM) and hypertension | - | significantly reduced | #2 |
DASH diet (DASH) | decrease | BMI | older patients with type 2 diabetes mellitus (T2DM) and hypertension | - | significantly reduced | #3 |
DASH diet (DASH) | decrease | waking diastolic pressures on ambulatory blood pressure monitoring | older patients with type 2 diabetes mellitus (T2DM) and hypertension | - | significantly reduced | #4 |
DASH diet with physical activity guidance (DASHPED) | decrease | weight | older patients with type 2 diabetes mellitus (T2DM) and hypertension | - | significantly reduced | #5 |
DASH diet with physical activity guidance (DASHPED) | decrease | BMI | older patients with type 2 diabetes mellitus (T2DM) and hypertension | - | significantly reduced | #6 |
DASH diet with physical activity guidance (DASHPED) | decrease | waking diastolic pressures on ambulatory blood pressure monitoring | older patients with type 2 diabetes mellitus (T2DM) and hypertension | - | significantly reduced | #7 |
DASH diet with physical activity guidance (DASHPED) | decrease | sleeping diastolic pressure | older patients with type 2 diabetes mellitus (T2DM) and hypertension | - | trend of reduced | #8 |
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED) | no change | weight | older patients with type 2 diabetes mellitus (T2DM) and hypertension | - | did not differ | #9 |
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED) | no change | BMI | older patients with type 2 diabetes mellitus (T2DM) and hypertension | - | did not differ | #10 |
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED) | no change | muscle mass | older patients with type 2 diabetes mellitus (T2DM) and hypertension | - | did not differ | #11 |
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED) | no change | body fat | older patients with type 2 diabetes mellitus (T2DM) and hypertension | - | did not differ | #12 |
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED) | no change | waist-hip ratio | older patients with type 2 diabetes mellitus (T2DM) and hypertension | - | did not differ | #13 |
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED) | no change | glycemic control | older patients with type 2 diabetes mellitus (T2DM) and hypertension | - | did not differ | #14 |
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED) | no change | lipid profile | older patients with type 2 diabetes mellitus (T2DM) and hypertension | - | did not differ | #15 |
DASH diet (DASH) vs DASH diet with physical activity guidance (DASHPED) | no change | insulin sensitivity | older patients with type 2 diabetes mellitus (T2DM) and hypertension | - | did not differ | #16 |
BACKGROUND AND AIMS: To evaluate the effect of lifestyle modification by adopting a DASH diet, with and without physical activity guidance, on blood pressure, glycemic control, lipid profile, weight, and body composition in older patients with type 2 diabetes mellitus (T2DM) and hypertension. METHODS AND RESULTS: For this randomized clinical trial, we recruited patients aged 60 years or older with T2DM and uncontrolled hypertension. One group (DASH) received only DASH dietary guidance, while the other group (DASHPED) received dietary guidance and encouragement to walk with a pedometer. Outcomes of interest were (1) blood pressure, (2) physical activity, (3) weight, body mass index (BMI), and body composition, and (4) biochemical variables. Measurements were taken at baseline and 16 weeks after the intervention. We included 35 patients in the analysis. At the end of the study, the DASHPED group had an mean increase in physical activity of 1721 steps/day. Both groups displayed significantly reduced weight, BMI, and waking diastolic pressures on ambulatory blood pressure monitoring after the intervention. A trend of reduced sleeping diastolic pressure was found in the DASHPED group. Changes in weight, BMI, muscle mass, body fat, waist-hip ratio, glycemic control, lipid profile, and insulin sensitivity did not differ between the groups. CONCLUSION: There was no difference in outcomes between the group that only dieted and the group that also performed increased physical activity, despite a significant increase in exercise. This reinforces the importance of dietary changes in immediate blood pressure control.