Supraspinal melatonin MT
Journal of pineal research
November 1, 2022
Luca Posa et al. (12 authors)
Journal ArticleHuman StudyMolecular Study
Extracted Claims (3)
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Melatonin | decrease | insulin secretion | human islet β-cells | - | reduced | #1 |
Melatonin | decrease | glucose tolerance | human carriers of the MTNR1B G allele | - | impaired | #2 |
Melatonin | increase | type 2 diabetes risk | human carriers of the MTNR1B G allele | - | increased | #3 |
Abstract
Melatonin, through its G protein-coupled receptor (GPCR) (MTNR1B gene) MT
Medical Subject Headings (MeSH)
MiceAnimalsRatsReceptors, Opioid, muMelatoninNarcotic AntagonistsReceptors, Opioid, deltaAnalgesics, OpioidEnkephalinsNaloxoneNeuralgia
Study Links
PubMed ID35996205
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