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Dietary Management of Type 1 Diabetes Mellitus with Celiac Disease.

Current diabetes reviews
January 1, 2023
Marah Attallah Al-Majali et al. (3 authors)
ReviewJournal ArticleHuman Study
Study Details

Study Goal

The researchers aimed to review the clinical features, diagnostic considerations, and dietary management of gluten-free diets (GFD) in patients with type 1 diabetes mellitus and celiac disease, focusing on glycemic control and growth rate.

Results Summary

The study found that most gluten-free foods have a high glycemic index, complicating dietary control for patients with type 1 diabetes and celiac disease. A low-carbohydrate diet was noted to improve glycemic control and insulin parameters, but few studies have examined the effects of a carbohydrate-count gluten-free diet on glycemic control, growth rate, and quality of life.

Population

Patients with type 1 diabetes mellitus and celiac disease, particularly children.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (12)
InterventionDirectionEndpointPopulationDosageImpactClaim #
diet management
decrease
elevated HbA1c levels
child with type 1 diabetes and celiac disease
-
could improve
#1
diet management
neutral
glycemic control
patients with type 1 diabetes mellitus and celiac disease
-
importance of
#2
diet management
neutral
growth rate
patients with type 1 diabetes mellitus and celiac disease
-
importance of
#3
carbohydrate count gluten-free diet
neutral
glycemic control
patients with type 1 diabetes mellitus and celiac disease
-
effects of
#4
carbohydrate count gluten-free diet
neutral
growth rate
patients with type 1 diabetes mellitus and celiac disease
-
effects of
#5
carbohydrate count gluten-free diet
neutral
quality of life
patients with type 1 diabetes mellitus and celiac disease
-
effects of
#6
dietary intervention
neutral
normal blood glucose levels
-
-
helps to achieve and maintain
#7
dietary intervention
neutral
normal blood pressure levels
-
-
helps to achieve and maintain
#8
dietary intervention
neutral
healthy lipid profile
-
-
helps to achieve and maintain
#9
dietary intervention
neutral
healthy body weight
-
-
helps to achieve and maintain
#10
low-carbohydrate diet
increase
glycemic control
-
-
had the greatest effect on improving
#11
low-carbohydrate diet
increase
insulin parameters
-
-
had the greatest effect on improving
#12
Abstract

Celiac disease is diagnosed more commonly with type 1 diabetes, and the most problematic aspect for a child with type 1 diabetes and celiac disease is that most GFD foods have a high glycemic index, while low glycemic index foods are recommended for type 1 diabetes mellitus. As a result, dietary controls become more difficult. Diet management could improve the elevated HbA1c levels. The aim of this review is to illustrate the clinical features and diagnostic considerations, as well as current knowledge of common pathogenic features such as genetics, environmental risk factors, and the gut microbiome of type 1 diabtes and celiac disease. Also, the importance of diet management on glycemic control and growth rate in patients with type 1 diabetes mellitus and celiac disease has been discussed. PubMed and Google Scholar databases were searched. Reports published from the years 1969 to 2021 focused on the role of type 1 diabetes mellitus and celiac disease, and examined the types of diet on glycemic control, growth rate, and quality of life. Only a few studies on the effects of a carbohydrate count gluten-free diet on glycemic control, growth rate, and quality of life in patients with type 1 diabetes mellitus and celiac disease have been conducted. There have been few studies showing that dietary intervention helps to achieve and maintain normal blood glucose and blood pressure levels, a healthy lipid profile, and a healthy body weight. Studies stated that a low-carbohydrate diet had the greatest effect on improving glycemic control and insulin parameters.

Medical Subject Headings (MeSH)
ChildHumansDiabetes Mellitus, Type 1Celiac DiseaseQuality of LifeDiet, Gluten-FreeGlycemic Index
Study Links
Quality Scores
SafetyNot Assessed
Efficacy65/10
Quality70/10
Citation Metrics
Total Citations3
Citations/Year1.5
Relative Citation Ratio1.11
NIH Percentile54%
Research Impact Scores
APT Score0.25
Weight Score2.39
Normalized Score0.60
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