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Exclusive Breastfeeding and Vitamin D Supplementation: A Positive Synergistic Effect on Prevention of Childhood Infections?

International journal of environmental research and public health
January 1, 1970
Raffaele Domenici et al. (2 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the benefits of breastfeeding for infant health, particularly its role in reducing infection risk and nutrient adequacy, while highlighting the need for vitamin D supplementation.

Results Summary

Breastfeeding is associated with reduced risk of viral and bacterial infections and provides optimal nutrients for infant growth, except for vitamin D, which requires supplementation during the first year to prevent deficiency.

Population

Infants, particularly those exclusively breastfed.

Effective Dosage

Vitamin D supplementation recommended (specific dosage not provided).

Duration

First year of life.

Interactions

None mentioned.

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Breastfeeding
decrease
viral and bacterial infections
infants
-
has been associated with a reduced risk
#1
Breast milk
neutral
nutrients needed to promote infant growth
infants
-
contains the perfect amount
#2
exclusive breastfeeding
increase
vitamin D deficiency
infants
-
is a risk factor for
#3
vitamin D supplementation
decrease
vitamin D deficiency
infants
-
should be supplemented
#4
Abstract

Human milk is the best food for infants. Breastfeeding has been associated with a reduced risk of viral and bacterial infections. Breast milk contains the perfect amount of nutrients needed to promote infant growth, except for vitamin D. Vitamin D is crucial for calcium metabolism and bone health, and it also has extra-skeletal actions, involving innate and adaptive immunity. As exclusive breastfeeding is a risk factor for vitamin D deficiency, infants should be supplemented with vitamin D at least during the first year. The promotion of breastfeeding and vitamin D supplementation represents an important objective of public health.

Medical Subject Headings (MeSH)
Breast FeedingDietary SupplementsFemaleHumansInfantMilk, HumanVitamin DVitamin D Deficiency
Study Links
Quality Scores
Safety95
Efficacy90/10
Quality85/10
Citation Metrics
Total Citations8
Citations/Year2.7
Relative Citation Ratio1.20
NIH Percentile57.1%
Research Impact Scores
APT Score0.50
Weight Score1.69
Normalized Score0.91
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